Abstract
The present report describes a 54-year-old woman with a history of recurrent thromboembolic events. The clinical and physical examination led to suspect Cushing’s syndrome. Screening tests (urinary free Cortisol excretion and 1 mg dexamethasone) were inconclusive, but a detailed endocrine work up confirmed the presence of ACTH-dependent hypercortisolism. The patient was cured by the removal of a ACTH-secreting microadenoma by transsphenoidal route. The present case provides a clinical demonstration of a previous experimental evidence that a hypercoagulable state is present in Cushing’s syndrome.
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La Brocca, A., Terzolo, M., Pia, A. et al. Recurrent thromboembolism as a hallmark of Cushing’s syndrome. J Endocrinol Invest 20, 211–214 (1997). https://doi.org/10.1007/BF03346905
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DOI: https://doi.org/10.1007/BF03346905