Skip to main content
Log in

A national study of iodine status in Albania

  • Original Articles
  • Published:
Journal of Endocrinological Investigation Aims and scope Submit manuscript

Abstract

Objective: The aim of the study was to determine the iodine status in Albania following 11 yr of iodine prophylaxis and to evaluate factors influencing the outcome. Design: Eight hundred and forty children, aged 6–13 yr, living in 4 different regions and 365 pregnant women living in the same areas, were enrolled for the study. The prevalence of goiter was assessed by palpation and ultrasound imaging and the urinary iodine and the iodine concentration in the salt of different commercial brands were evaluated. Presence of goiter in the family and their eating habits were also investigated as well as the use of iodized salt in the household. Main outcome: In children, the prevalence of goiter was 57.6% by palpation and 24.4% by ultrasound imaging. Median urinary iodine was 86.2 μg/l, with pronounced geographical variations (range 3.52–1079 μg/l). In particular, 29.1 % of the children had urinary iodine <50 μg/l and 57.1% <100 μg/l. In pregnant women, the median urinary iodine was 85 μg/l. Median iodine concentration in household iodized salt was 21.2 mg/kg, with 60.3% of the brands being adequately and 39.7% non-adequately iodized. Almost all families (99.6%) claimed to use iodized salt. Conclusion: Despite the introduction of iodine prophylaxis, there is still a mild iodine deficiency in Albania, particularly in the inner mountainous areas.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  1. Kalo I, Karafili L. IDD in Albania. Poster presented at Brussels Symposium on IDD. 1992.

  2. Current IDD status database ICCIDD: http://www.people.virginia.edu/~jtd/iccidd/mi/idd_003.htm.

  3. Bardhoshi A, et al. Iodine Deficiency Disorders in Albania. IDD Newsletter 1997, 13.

  4. Zimmermann MB, Bridson J, Bozo M, et al. Severe iodine deficiency in Southern Albania. Int J Vitam Nutr Res 2003, 73: 347–50.

    Article  PubMed  CAS  Google Scholar 

  5. WHO. Assessment of Iodine Deficiency Disorders and Monitoring their Elimination. A guide for programme managers, 3nd Ed. Geneva: WHO, 2007. 6. Center for Disease Control and Prevention. CDC Growth Charts. www.CDC.gov/growthcharts.

    Google Scholar 

  6. WHO, UNICEF, ICCIDD. Indicators for assessing Iodine Deficiency Disorders and their control through salt iodization. Geneva: WHO, 1992.

    Google Scholar 

  7. WHO. Expanded Program on Immuniziation. The EPI coverage Survey, training for mid level managers. Geneva: WHO, 1991.

    Google Scholar 

  8. WHO. Description and comparison of the methods of cluster sampling and lot quality assurance sampling to assess immunization coverage. Geneva: WHO, 2001. 10. SAS Enterprise Guide 4.1 (Cary, NC, USA).

  9. Zimmermann MB, Connolly K, Bozo M, Bridson J, Rohner F, Grimci L. Iodine supplementation improves cognition in iodine-deficient schoolchildren in Albania: a randomized, controlled, double-blind study. Am J Clin Nutr 2006, 83: 108–14.

    PubMed  CAS  Google Scholar 

  10. Stilwell G, Reynolds PJ, Parameswaran V, Blizzard L, Greenaway TM, Burgess JR. The influence of gestational stage on urinary iodine excretion in pregnancy. J Clin Endocrinol Metab 2008, 93: 1737–42.

    Article  PubMed  CAS  Google Scholar 

  11. Qian M, Wang D, Watkins WE, et al. The effects of iodine on intelligence in children: a meta-analysis of studies conducted in China. Asia Pac J Clin Nutr 2005, 14: 32–42.

    PubMed  CAS  Google Scholar 

  12. Tai M. The devastating consequence of iodine deficiency. Southeast Asian J Trop Med Public Health 1997, 28 (Suppl 2): 75–7.

    PubMed  Google Scholar 

  13. O’Donnell KJ, Rakeman MA, Zhi-Hong D, et al. Effects of iodine supplementation during pregnancy on child growth and development at school age. Dev Med Child Neurol 2002, 44: 76–81.

    Article  PubMed  Google Scholar 

  14. Zimmermann MB, Hess SY, Molinari L, et al. New reference values for thyroid volume by ultrasound in iodine-sufficient schoolchildren: a World Health Organization/Nutrition for Health and Development Iodine Deficiency Study Group Report. Am J Clin Nutr 2004, 79: 231–7.

    PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to F. Franzellin MD.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Franzellin, F., Hyska, J., Bushi, E. et al. A national study of iodine status in Albania. J Endocrinol Invest 32, 533–537 (2009). https://doi.org/10.1007/BF03346502

Download citation

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF03346502

Key-words

Navigation