Abstract
Objective: To investigate the effects of an 8-month multidisciplinary weight-control program, including 2 h/week of moderate physical activity, nutritional education lessons and psychological follow-up, on body composition and lipid oxidation rate during exercise in obese children. Design: Nineteen (7 boys and 12 girls) obese children, aged 8–12 yr [mean body mass index (BMI) z-score: 2.3 and fat mass: 35.8%] participated in this study. Before and at the end of the weight-control period body composition was assessed by bioelectrical impedance, lipid oxidation rate by indirect calorimetry during a graded exercise test, and time devoted to various activities and energy intake in free-living conditions by questionnaire. Results: All children completed the study, at the end of which BMI decreased significantly by mean 0.6±0.5 and 0.5±0.8 kg/m2, in boys and girls, respectively (p<0.05), and fat mass (FM) decreased by 1.7±2.8 and 1.4±1.3 kg in boys and girls, respectively (p<0.05). In addition, lipid oxidation rate during exercise increased significantly throughout the graded exercise test up to 21% at maximal lipid oxidation rate which happened at 48±5% of maximal oxygen uptake (VO2max), corresponding to 64±5% of maximal heart rate. Time spent at sedentary and very light physical activities decreased (p<0.001) to the benefit of recreational activities at home. Conclusions: Multi-disciplinary weight-control program, with moderate-intensity physical activities, induced decreases in FM without decreases in free FM, increases in VO2max, lipid oxidation rate during exercise, and time devoted to recreational activities in free-living conditions.
Similar content being viewed by others
References
Lobstein T, Baur L, Uauy R; IASO International Obesity TaskForce. Obesity in children and young people: a crisis in public health. Obes Rev 2004, 5 (Suppl 1): 4–85.
DuRant RH, Baranowski T, Rhodes T, et al. Association among serum lipid and lipoprotein concentrations and physical activity, physical fitness, and body composition in young children. J Pediatr 1993, 123: 185–92.
Pflieger KL, Treiber FA, Davis H, McCaffrey FM, Raunikar RA, Strong WB. The effect of adiposity on children’s left ventricular mass and geometry and haemodynamic responses to stress. Int J Obes Relat Metab Disord 1994, 18: 117–22.
Dietz WH. Health consequences of obesity in youth: childhood predictors of adult disease. Pediatrics 1998, 101: 518–25.
Achten J, Jeukendrup AE. Optimizing fat oxidation through exercise and diet. Nutrition 2004, 20: 716–27.
De Glisezinski I, Crampes F, Harant I, et al. Endurance training changes in lipolytic responsiveness of obese adipose tissue. Am J Physiol 1998, 275: E951–6.
Stich V, de Glisezinski I, Galitzky J, et al. Endurance training increases the beta-adrenergic lipolytic response in subcutaneous adipose tissue in obese subjects. Int J Obes Relat Metab Disord 1999, 23: 374–81.
Barbeau P, Gutin B, Litaker M, Owens S, Riggs S, Okuyama T. Correlates of individual differences in body-composition changes resulting from physical training in obese children. Am J Clin Nutr 1999, 69: 705–11.
Sothern MS, Loftin M, Suskind RM, Udall JN Jr, Blecker U. The impact of significant weight loss on resting energy expenditure in obese youth. J Investig Med 1999, 47: 222–6.
Lazzer S, Boirie Y, Montaurier C, Vernet J, Meyer M, Vermorel M. A weight reduction program preserves fat-free mass but not metabolic rate in obese adolescents. Obes Res 2004, 12: 233–40.
Luciano A, Bressan F, Zoppi G. Body mass index reference curves for children aged 3–19 years from Verona, Italy. Eur J Clin Nutr 1997, 51: 6–10.
Borg GA. Psychophysical bases of perceived exertion. Med Sci Sports Exerc 1982, 14: 377–81.
Tanner JM. Growth at adolescence. 2nd ed. Oxford, UK: Blackwell, 1961.
Sempé M, Pedron G, Roy-Pernot MP. Auxologie: méthode et séquences. Paris: Laboratoire Théraplix, 1979.
Lukaski HC, Bolonchuk WW, Hall CB, Siders WA. Validation of tetrapolar bioelectrical impedance method to assess human body composition. J Appl Physiol 1986, 60: 1327–32.
Lazzer S, Boirie Y, Meyer M, Vermorel M. Which alternative method to dual-energy X-ray absorptiometry for assessing body composition in overweight and obese adolescents? Arch Pediatr 2005, 12: 1094–101.
Achten J, Gleeson M, Jeukendrup AE. Determination of the exercise intensity that elicits maximal fat oxidation. Med Sci Sports Exerc 2002, 34: 92–7.
MacRae HS, Noakes TD, Dennis SC. Role of decreased carbohydrate oxidation on slower rises in ventilation with increasing exercise intensity after training. Eur J Appl Physiol Occup Physiol 1995, 71: 523–9.
Frayn KN. Calculation of substrate oxidation rates in vivo from gaseous exchange. J Appl Physiol 1983, 55: 628–34.
Burke L, Deakin V. Protein and amino acid needs for training and bulking up. In: Clinical Sports Nutrition. Roseville, Australia: Mc Graw-Hill Company 2000, 90–123.
Lazzer S, Meyer F, Meyer M, Boirie Y, Vermoret M. Assessment on the usual physical activity in overweight and obese adolescents. Presse Med 2004, 33: 1255–9.
Vermorel M, Vernet J, Bitar A, Fellmann N, Coudert J. Daily energy expenditure, activity patterns, and energy costs of the various activities in French 12–16-yr-old adolescents in free living conditions. Eur J Clin Nutr 2002, 56: 819–29.
Energy and protein requirements: report of joint FAO/WHO/UNU expert consultation World Health Organ Technical Report Series 724. Geneva, Switzerland, 1985.
Lazzer S, Boirie Y, Itier A, Brandolini M, Meyer M, Vermorel M. Assessment of energy and nutrient intakes in obese and post-obese adolescents: validation of the SU.VI.MAX iconographic method against the weighed diet record method. Cahiers Nutrition Diététique 2005, 40: 45–51.
Istituto Scotti-Bassani. Atlante ragionato di alimentazione (Atlas of feeding). Milano, 1992.
Carnovale E, Marletta L. Tabelle di composizione degli alimenti (Food composition tables). Milano: EDRA medical publishing, 2000.
Houtkooper LB, Lohman TG, Going SB, Howell WH. Why bioelectrical impedance analysis should be used for estimating adiposity. Am J Clin Nutr 1996, 64 (3 Suppl): 436S–48S.
Wabitsch M, Braun U, Heinze E, et al. Body composition in 5–18-y-old obese children and adolescents before and after weight reduction as assessed by deuterium dilution and bioelectrical impedance analysis. Am J Clin Nutr 1996, 64: 1–6.
Schaefer F, Georgi M, Zieger A, Schärer K. Usefulness of bioelectric impedance and skinfold measurements in predicting fat-free mass derived from total body potassium in children. Pediatr Res 1994, 35: 617–24.
McConnell TR. Cardiorespiratory assessment of apparently healthy population: ACSM’s resource manual for guidelines for exercise testing and prescription. Baltimore: Williams&Wilkins, 2001.
Dériaz O, Dumont M, Bergeron N, Despres JP, Brochu M, Prud’homme D. Skeletal muscle low attenuation area and maximal fat oxidation rate during submaximal exercise in male obese individuals. Int J Obes Relat Metab Disord 2001, 25: 1579–84.
Steffan HG, Elliott W, Miller WC, Fernhall B. Substrate utilization during submaximal exercise in obese and normal-weight women. Eur J Appl Physiol Occup Physiol 1999, 80: 233–9.
Maffeis C, Zaffanello M, Pellegrino M, et al. Nutrient oxidation during moderately intense exercise in obese prepubertal boys. J Clin Endocrinol Metab 2005, 90: 231–6. Epub 2004 Oct 13.
Brandou F, Savy-Pacaux AM, Marie J, et al. Impact of high- and low-intensity targeted exercise training on the type of substrate utilization in obese boys submitted to a hypocaloric diet. Diabetes Metab 2005, 31: 327–35.
Schrauwen P, van Aggel-Leijssen DP, Hul G, et al. The effect of a 3- month low-intensity endurance training program on fat oxidation and acetyl-CoA carboxylase-2 expression. Diabetes 2002, 51: 2220–6.
Goodpaster BH, Wolfe RR, Kelley DE. Effects of obesity on substrate utilization during exercise. Obes Res 2002, 10: 575–84.
Holloszy JO, Coyle EF. Adaptations of skeletal muscle to endurance exercise and their metabolic consequences. J Appl Physiol 1984, 56: 831–8.
Gollnick PD. Metabolism of substrates: energy substrate metabolism during exercise and as modified by training. Fed Proc 1985, 44: 353–7.
Brandou F, Savy-Pacaux AM, Marie J, Brun JF, Mercier J. Comparison of the type of substrate oxidation during exercise between pre and post pubertal markedly obese boys. Int J Sports Med 2006, 27: 407–14.
van Aggel-Leijssen DP, Saris WH, Wagenmakers AJ, Senden JM, van Baak MA. Effect of exercise training at different intensities on fat metabolism of obese men. J Appl Physiol 2002, 92: 1300–9.
Kanaley JA, Cryer PE, Jensen MD. Fatty acid kinetic responses to exercise. Effects of obesity, body fat distribution, and energy-restricted diet. J Clin Invest 1993, 92: 255–61.
Epstein LH, Valoski AM, Vara LS, et al. Effects of decreasing sedentary behavior and increasing activity on weight change in obese children. Health Psychol 1995, 14: 109–15.
Doak CM, Visscher TL, Renders CM, Seidell JC. The prevention of overweight and obesity in children and adolescents: a review of interventions and programmes. Obes Rev 2006, 7: 111–36.
DeLany JP, Bray GA, Harsha DW, Volaufova J. Energy expenditure and substrate oxidation predict changes in body fat in children. Am J Clin Nutr 2006, 84: 862–70.
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Lazzer, S., Molin, M., Stramare, D. et al. Effects of an eight-month weight-control program on body composition and lipid oxidation rate during exercise in obese children. J Endocrinol Invest 31, 509–514 (2008). https://doi.org/10.1007/BF03346399
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/BF03346399