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Macroprolactinoma associated with Cushing’s disease, successfully treated with cabergoline

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Abstract

Multiple pituitary hormone hypersecretions have already been described, but the co-occurrence of PRL and ACTH excess is very rare. To our knowledge, medical treatment with cabergoline only, avoiding pituitary surgery and radiotherapy in this type of tumor has never been reported before. This case report deals with a 31-yr-old man affected with a macroprolactinoma associated with a florid clinical image of Cushing’s disease. Normalization of the prolactin levels and the disappearance of clinical and biochemical features of Cushing’s disease were obtained after administration of medical treatment only.

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Authors and Affiliations

  1. Department of Endocrinology and Metabolism, University Hospital, Gent, Belgium

    Guy T’sjoen, J. Van De Saffele, R. Rubens & M. Vandeweghe

  2. Department of Endocrinology and Metabolism, Jan Palfijn Hospital, Gent, Belgium

    I. Defeyter

Authors
  1. Guy T’sjoen
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  2. I. Defeyter
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  3. J. Van De Saffele
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  4. R. Rubens
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  5. M. Vandeweghe
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Correspondence to Guy T’sjoen.

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T’sjoen, G., Defeyter, I., Van De Saffele, J. et al. Macroprolactinoma associated with Cushing’s disease, successfully treated with cabergoline. J Endocrinol Invest 25, 172–175 (2002). https://doi.org/10.1007/BF03343983

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  • DOI: https://doi.org/10.1007/BF03343983

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