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Hyperphagia and self-mutilation in Prader-Willi syndrome: Psychopharmacological issues

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Abstract

This study focused in the treatment of two major Prader-Willi symptoms: hyper phagia and self-injurious behavior (SIB). Four patients participated in a four-year study with monthly follow-ups. Patients lived in a behaviorally structured environment, and were treated with selective serotonin reuptake blockers and phenothiazines. Psychopharmacological inter vention improved SIB symptoms, but was ineffective to control appetite satiation.

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Yaryura-Tobias, J.A., Grunes, M.S., Bayles, M.E. et al. Hyperphagia and self-mutilation in Prader-Willi syndrome: Psychopharmacological issues. Eat Weight Disord 3, 163–167 (1998). https://doi.org/10.1007/BF03340005

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