Abstract
Evaluation of hip, knee and hand osteoarthritis (OA) involves clinical and radiological outcome measures. Clinical, mainly visual analog scale (VAS) for pain, algofunctional or Lequesne’s indices for hip and knee OA, Western Ontario and Mac Master Universities OA Index (WOMAC) for hip and knee OA, Dreiser’s functional index for hand OA and some quality-of-life (QoL) indices are presented and discussed. Their utility is considered according to various uses: assessment of OA severity and course in therapeutic trials, in daily practice, as a help for surgical decision, and with regard to QoL as instruments for establishing the place of OA among differing chronic rheumatic conditions. Radiological assessment methods, especially for potential structure-modifying drug trials, mainly involve either manual measurement of joint space narrowing on radiographs over a period of several years, or measurement on X-ray digitized images. Last but not least, to conclude this review, we propose a selection of the most rapid and practical instruments allowing OA assessment in daily practice, with appropriate comments.
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References
Huskisson EC. Measurement of pain. Lancet 1974; 4: 1127–31.
Lequesne M. Clinical features diagnostic criteria, functional assessments and radiological classifications of osteoarthritis (excluding the spine). In Huskisson EC, Katona G, Eds. New Trends in Osteoarthritis. Rheumatology. Annual Review. Basel: Karger. 1982: 1–10.
Lequesne MG, Mery C, Samson M, Gerard P. Indices of severity for osteoarthritis of the hip and knee: validation -value in comparison with other assessment tests. Scand J Rheumatol 1987; Suppl 65: 85–9.
Bellamy N, Buchanan WW, Goldsmith CH, Campbell J, Stitt L. Validation study of WOMAC: A health status instrument for measuring clinically important patients with osteoarthritis of the hip or knee. J Rheumatol 1988; 15: 1833–40.
Dreiser RL, Maheu E, Guillou GB, Caspard H, Grouin JM. Validation of an algofunctional index for osteoarthritis of the hand. Rev Rheum (Engl Ed) 1995; 62(Suppl 1): 43S–53.
Bellamy N, Haraoui B, Buchbinder R, et al. Development of a disease-specific health status measure for hand osteoarthritis clinical trials. I. Assessment of symptom dimensionality. Scand J Rheumatol 1996; 23 (Suppl 106): 5 (Abstract).
Lequesne MG. The algofunctional indices for hip and knee osteoarthritis. J Rheumatol 1997; 24: 779–81.
O’Reilly SC, Muir KR, Doherty M. Screening for pain in knee osteoarthritis: which question? Ann Rheum Dis 1996; 55: 931–3.
Altman R, Brandt K, Moskowitz R, et al. Design and conduct of clinical trials in patients with osteoarthritis. Recommendations from a task force of the Osteoarthritis Research Society. Osteoarthritis Cartilage 1996; 4: 217–43.
Bellamy N, Kirwan J, Boers M, et al. Recommendations for a core set of outcome measures for future Phase III clinical trials in knee, hip and hand osteoarthritis. Consensus development at OMERAT III. J Rheumatol 1997; 24: 799–802.
Dieppe P, Cushnaghan J, Jasani MK, McCrae F, Watt I. A two-year placebo controlled trial of NSAID therapy in OA of the knee joint. Br J Rheumatol 1993; 32: 595–600.
Obère J, Esdaile J M, Thorne A, et al. Multicenter randomized double-blind placebo controlled glucosamine discontinuation trial in osteoarthritis. Arthritis Rheum 2002; 45: S576 (Abstract).
Gérin P, Dazord A, Boissel JP, Hanouer MT, Moleur P, Chauvin F. L’évaluation de la qualité de vie dans les essais thérapeutiques. Aspects conceptuels et présentation d’un questionnaire. Thérapie 1989; 44: 353–64.
Pouchot J, Coste J, Guillemin F. Impact of osteoarthritis on quality of life. In Reginster JY, Pelletier J-P, Martel-Pelletier J, Henrotin Y. Eds. Osteoarthritis: clinical and experimental aspects. Berlin: Springer, 1999: 331–55.
Ware JE Jr, Sherbourne CD. The MOS 36-item short-form survey (SF-36). I. Conceptual framework and item selection. Med Care 1992; 30: 473–83.
Hunt SM, McKenna SP, McEwen J, Williams P, Papp E. The Nottingham Health Profile. Subjective health status and medical consultations. Soc Sci Med 1981; 15A: 221–9.
Pincus T, Summey JA, Soraci S Jr, Wallstone KA, Hummon NP. Assessment of patient satisfaction in activities of daily living using a modified Stanford Health Assessment questionnaire. Arthritis Rheum 1983; 26: 1346–53.
Fries JF, Spitz PW, Young DY. The dimensions of health outcomes. The health assessment questionnaire. Disability and pain scale. J Rheumatol 1982; 9: 789–93.
Meenan RF, Mason JH, Anderson JJ, Guccione AA, Kazis LE. AIMS2. The content and properties of a revised and expanded Arthritis Impact Measurement Scales Health Status Questionnaire. Arthritis Rheum 1992; 35: 1–10.
Carr A. Problems in measuring or interpreting change in patient outcomes. Osteoarthritis Cartilage 2002; 10: 503–5.
Felson DT. The verdict favors non-steroidal antiinflammatory drugs for treatment of osteoarthritis and a plea for more evidence on other treatments. Arthritis Rheum 2001; 44: 1477–80.
Dougados M, Nguyen M, Berdah L, et al. Evaluation of the structure modifying effects of diacerhein in hip osteoarthritis. ECODIAH. a three-year placebo controlled trial. Arthritis Rheum 2001; 44: 2534–47.
Wiklund I, Romanus B. A comparison of quality of life before and after arthroplasty in patients who had arthrosis of the hip joint. J Bone Joint Surg 1991; 73 A: 765–9.
Callahan LF, Smith WJ, Pincus T. Self report questionnaires in five rheumatic diseases. Arthritis Care Res 1989; 2: 122–31.
Altman R, Alarcon G, Appelrough D, et al. The American College of Rheumatology criteria for the classification and reporting of osteoarthritis of the hand. Arthritis Rheum 1990; 33: 1601–10.
Group for the Respect of Ethics and Excellence in Science (GREES: Osteoarthritis section). Recommendations for the registration of drugs in the treatment of osteoarthritis. Ann Rheum Dis 1996; 55: 552–7.
Maheu E, Dewailly J. Weekly self-assessment of painful joints in hand osteoarthritis (HOA): a new assessment tool. Preliminary validation study. Arthritis Rheum 1997; 40 (Suppl): S236 (Abstract).
Lequesne MG, Maheu E. Methodology of clinical trials in hand osteoarthritis: conventional and proposed tools. Osteoarthritis Cartilage 2000; 8(Suppl A): S64–9.
Dreiser RL, Maheu E, Guillou GB. Sensitivity to change of the functional index for hand osteoarthritis. Osteoarthritis Cartilage 2000; 8(Suppl A): S25–8.
Poiraudeau S, Chevalier X, Conrozier T, et al. Reliability, validity and sensitivity to change of the Cochin Hand functional disability scale in hand osteoarthritis. Osteoarthritis Cartilage 2001; 9: 570–7.
Mejjad O, Maheu E. Therapeutic trials in hand osteoarthritis: a critical review. Osteoarthritis Cartilage 2000; 8(Suppl A): S57–63.
Lequesne M, Cadet C, Winkler P, Rodriguez P, Wilhelm F. How rapid is the narrowing of the joint space in primary osteoarthritis of the hip within 3 years? Validity of its measure for a long-term trial. XVII ILAR Congress Rheum. 1989: 52 (Abstract F 28).
Lequesne M. Quantitative measurements of joint space during progression of osteoarthritis: “chondrometry”. In Kuettner K, Goldberg V, Eds. Osteoarthritic disorders. Rosemont, Ill: American Academy of Orthopaedic Surgeons, 1995; 427–44.
Conrozier T, Lequesne M, Favret H, et al. Measurement of the radiological hip joint space width. An evaluation of various methods of measurement. Osteoarthritis Cartilage 2001; 9: 281–6.
Ravaud P, Giraudeau B, Auleley G, et al. Radiographic assessment of knee osteoarthritis: reproducibility and sensitivity to change. J Rheumatol 1996; 23: 1756–64.
Kellgren JH, Lawrence JS. Radiologic assessment of osteoarthrosis. Ann Rheum Dis 1957; 16: 494–501.
Kallman DA, Wigley FM, Scott WW, Hochberg MC, Tobin JD. New radiographic grading scales for osteoarthritis of the hand. Arthritis Rheum 1989; 32: 1584–91.
Kallman DA, Wigley FM, Scott WW Jr., Hochberg MC, Tobin JD. The longitudinal course of hand osteoarthritis in a male population. Arthritis Rheum 1990; 33: 1323–32.
Verbruggen G, Veys EM. Numerical scoring systems for the anatomic evolution of osteoarthritis of the finger joints. Arthritis Rheum 1996; 39: 308–20.
Verbruggen G, Veys EM. Erosive and non erosive hand osteoarthritis. Use and limitations of two scoring systems. Osteoarthritis Cartilage 2000; 8(Suppl A): S45–54.
Maheu E, Gueneugues S, Cadet C, Ravaud Ph, Dougados M. Sensitivity to change of 4 radiological scoring methods in hand osteoarthritis. Arthritis Rheum 2000; 43: S338 (Abstract).
Maheu E, Gueneugues S, Cadet C, Ravaud Ph, Dougados M. Reproducibility of 4 radiological scoring methods to assess the severity and progression of hand OA. Arthritis Rheum 2000; 43: S338 (Abstract).
Lequesne M. La douleur et le handicap dans l’arthrose. Mesures cliniques. Rhéumatologie 2000; 52: 20–5.
Pincus T, Swearingen C, Wolfe F. Toward a multidimensional health assessment questionnaire (MDHAQ). Arthritis Rheum 1999; 42: 2220–30.
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Lequesne, M.G., Maheu, E. Clinical and radiological evaluation of hip, knee and hand osteoarthritis. Aging Clin Exp Res 15, 380–390 (2003). https://doi.org/10.1007/BF03327359
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DOI: https://doi.org/10.1007/BF03327359