Article PDF
References
Hayflick L, Moorhead P. The serial cultivation of human diploid cell strains. Exp Cell Res 1961; 25: 585–621.
Cristofalo VJ, Pignolo RJ, Allen RG, Martin BG, Beck JC. Relationship between donor age and replicative lifespan of human cells in culture. Proc Natl Acad Sci USA 1998; 95: 10613–9.
Hayflick L. Aging under glass. Exp Gerontol 1970; 5: 291–303.
Hayflick L. The cell biology of human aging. N Engl J Med 1976; 295: 1302–8.
Pignolo RJ, Masoro EJ, Nichols WW, Bradt CI, Cristofalo VJ. Skin fibroblasts from aged Fischer 344 rats undergo similar changes in replicative life span but not immortalization with caloric restriction of donors. Exp Cell Res 1998; 95: 10614–9.
Cristofalo VJ, Pignolo RJ. Cell culture as a model. In Masoro EJ, Ed. Handbook of Physiology, section 11. Aging. New York: Oxford University Press, 1995: 53–82.
Adelman RC, Cristofalo VJ, Masoro EJ, Roberts J. The “Philadelphia Mafia”: Networking in the development of biological gerontology. Contemp Gerontol 2001; 8: 46–57.
Rohme D. Evidence for a relationship between longevity of mammalian species and life-spans of normal fibroblasts in vitro and erythrocytes in vivo. Proc Natl Acad Sci USA 1981; 78: 5007–13.
Lorenzini A, Tresini M, Austad SN, Cristofalo VJ. Cellular replication correlates with species body size and not longevity. Mech Ageing Dev 2005; 126: 1130–3.
Merry BJ. Oxidative stress and mitochondrial function with aging — the effects of caloric restriction. Aging Cell 2004; 3: 7–12.
Cristofalo VJ. Profile in gerontology, Leonard Hayflick, Ph.D. Contemp Gerontol 2003; 9: 83–6.
Martin GM, Sprague CA, Epstein CJ. Replicative life-span of cultivated human cells. Effects of donor’s age. tissue, and geonotype. Lab Invest 1970; 23: 86–92.
Bruce SA, Deamond SF, Ts’o PO. In vitro senescence of Syrian hamster mesenchymal cells of fetal to aged adult origin. Inverse relationship between in vivo donor age and in vitro proliferative capacity. Mech Ageing Dev 1986; 23: 151–73.
Goldstein S, Moerman EJ, Soeldner JS, Gleason RE, Barnett DM. Chronologic and physiologic age affect replicative life-span of fibroblasts from diabetic, prediabetic. and normal donors. Science 1978; 199: 781–2.
Stanley JF, Pye D, MacGregor A. Comparison of doubling numbers attained by cultured animal cells with life span of species. Nature 1975; 255: 158–9.
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Adelman, R., Hayflick, L., Masoro, E. et al. Vincent Cristofalo (1933–2006): Extraordinary Gerontologist. Aging Clin Exp Res 18, 463–469 (2006). https://doi.org/10.1007/BF03324845
Published:
Issue Date:
DOI: https://doi.org/10.1007/BF03324845