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A case of normal-pressure hydrocephalus associated with rheumatoid arthritis

Abstract

Rheumatoid arthritis may cause central nervous system complications by means of various mechanisms. We describe the case of a patient with a new diagnosis of rheumatoid arthritis (RA) complicated by normal-pressure hydrocephalus. After treatment with prednisone, the patient improved remarkably as regards mental status, urinary control and gait. We suggest that normal-pressure hydrocephalus may occur as an extra-articular manifestation of RA, caused by a pathogenic inflammatory mechanism. We analyse previous case reports describing a relationship between RA and normal-pressure hydrocephalus, and discuss potential mechanisms underlying this association.

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Correspondence to Chiara Catananti MD.

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Catananti, C., Mastropaolo, S., Calabrese, C. et al. A case of normal-pressure hydrocephalus associated with rheumatoid arthritis. Aging Clin Exp Res 22, 189–191 (2010). https://doi.org/10.1007/BF03324795

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  • DOI: https://doi.org/10.1007/BF03324795

Keywords

  • Dementia
  • hydrocephalus
  • rheumatoid arthritis