Aging Clinical and Experimental Research

, Volume 3, Issue 2, pp 193–196 | Cite as

Sleep disturbance and Alzheimer’s disease: Relationship to behavioral problems

  • George W. Rebok
  • B. W. Rovner
  • M. F. Folstein
Short Communication


We studied the sleep characteristics of 108 outpatients with probable Alzheimer’s disease and found that sleep disturbance was significantly related to daytime behavioral disturbance but not to cognitive impairment. Possible treatment strategies and neu-ropathological and neurochemical mechanisms are discussed. (Aging 3: 193-196, 1991)


Alzheimer’s disease behavioral problems neuroleptics sleep disturbance 


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Copyright information

© Editrice Kurtis s.r.l. 1991

Authors and Affiliations

  • George W. Rebok
    • 1
    • 2
  • B. W. Rovner
    • 2
  • M. F. Folstein
    • 2
  1. 1.Department of Mental HygieneThe Johns Hopkins UniversityBaltimoreUSA
  2. 2.Department of Psychiatry and Behavioral Sciences, and the Alzheimer’s Disease Research CenterThe Johns Hopkins University School of MedicineBaltimoreUSA

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