Sleep disturbance and Alzheimer’s disease: Relationship to behavioral problems
We studied the sleep characteristics of 108 outpatients with probable Alzheimer’s disease and found that sleep disturbance was significantly related to daytime behavioral disturbance but not to cognitive impairment. Possible treatment strategies and neu-ropathological and neurochemical mechanisms are discussed. (Aging 3: 193-196, 1991)
KeywordsAlzheimer’s disease behavioral problems neuroleptics sleep disturbance
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