Abstract
E conomic analysis of phase III clinical data indicates that anastrozole is a cost-effective treatment for patients with advanced breast cancer. Anastrozole was associated with an incremental cost-effectiveness ratio of £1608 per additional life-year gained, compared with megestrol, reported Mr JS Brown from Zeneca Pharmaceuticals, UK, at the First European Conference on the Economics of Cancer [ Belgium, Brussels; November 1997 ]. For most patients with advanced disease, the main aim of treatment is palliation, using endocrine therapy to restrict tumour growth and minimise symptoms. 1 Until recently, standard second-line therapy has been with either a progesterone (e.g. megestrol or medroxyprogesterone) or a nonspecific aromatase inhibitor (e.g. aminoglutethimide).
Additional information
1. Carlson RH. Aromatase inhibitors promising in advanced breast cancer. Inpharma 1107: 11-12, 4 Oct 1997
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Wright, T. Anastrozole cost effective in advanced breast cancer. Pharmacoecon. Outcomes News 147, 3–4 (1998). https://doi.org/10.1007/BF03277343
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DOI: https://doi.org/10.1007/BF03277343