Abstract
Aims: To evaluate and compare the efficacy of pea and halfpea portions of child formula fluoride (500ppm) toothpaste on artificially created enamel lesions in primary teeth. Methods: Sound primary incisors were painted with nail varnish, leaving a 1 mm wide window and then placed in a demineralising solution for 96 h to produce artificial carious lesions 60–100μm deep. The teeth were longitudinally sectioned (100μm thick) and divided into 3 groups. Group A: treated with a pea-sized portion of a non-fluoride containing toothpaste (1:3, toothpaste: deionized water), while Groups B and C were treated with half-pea-sized and pea-sized portions of a 500 ppm fluoride containing toothpaste, respectively. The pH-cycling model was utilized for 7 days. Results: Groups A and B lesions increased in depth by 60% while those in Group C increased by 19%. The mineral content of the surface zone decreased significantly in Groups A and B but not in Group C. Conclusion: Reduction of the amount of fluoride toothpaste to less than a pea-size in order to minimize the risk of fluorosis should be undertaken with caution because it may compromise the cariostatic effects of the toothpaste.
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References
Bentley EM, Ellwood RP, Davies RM. Fluoride ingestion from toothpaste by young children. Brit Dent J 1999;186:460–462.
Bloch-Zupan A. Is the fluoride concentration limit of 1,500 ppm in cosmetics (EU guideline) still up-to-date? Caries Res 2001;35(Suppl 1):22–25.
Burt BA. The changing patterns of systemic fluoride intake. J Dent Res 1992;71:1228–1237.
Davies GM, Worthington HV, Ellwood RP, Blinkhorn AS. An assessment of the cost effectiveness of a postal toothpaste programme to prevent caries among five-year-old children in the North West of England. Community Dent Health 2003;20(4):207–210.
Featherstone JD. Prevention and reversal of dental caries: role of low level fluoride. Community Dent Oral Epidemiol 1999;27:31–40.
Hara AT, Magalhaes CS, Serra MC, Rodrigues AL Jr. Cariostatic effect of fluoride-containing restorative systems associated with dentifrices on root dentin. J Dent 2002;30(5–6):205–212.
Heilman JR, Wefel JS, Pyrz JW. Development of a root caries pH cycling model. J Dent Res 1991;79:493.
Holt RD, Murray JJ. Developments in fluoride toothpastes—an overview. Community Dent Health 1997;14:4–10.
Itthagarun A, Wei SH, Wefel JS. Morphology of initial lesions of enamel treated with different commercial dentifrices using a pH cycling model: scanning electron microscopy observations. Int Dent J 1999;49(6):352–460.
Itthagarun A, Wei SH, Wefel JS. The effect of different commercial dentifrices on enamel lesion progression: an in vitro pH-cycling study. Int Dent J 2000;50(1):21–28.
Konig KG. New recommendations concerning the fluoride content of toddler toothpaste — consequences for systemic application of fluoride. Gesundheitswesen 2002;64:33–38.
Levy SM. Review of fluoride exposures and ingestion. Community Dent Oral Epidemiol 1994;2:173–180.
Levy SM, Kohout FJ, Kiritsy MC, Heilman JR, Wefel JS. Infants’ fluoride ingestion from water, supplements and dentifrice. J Am Dent Assoc 1995;126:1625–1632.
Levy SM, McGrady JA, Bhuridej P, et al. Factors affecting dentifrice use and ingestion among a sample of U.S. preschoolers. Pediatr Dent 2000;22:389–394.
Maltz M, Schoenardie AB, Carvalho JC. Dental caries and gingivitis in schoolchildren from the municipality of Porto Alegre, Brazil in 1975 and 1996. Clin Oral Invest 2001;5(3):199–204.
Marinho VC, Higgins JR Sheiham A, Logan S. Fluoride toothpastes for preventing dental caries in children and adolescents. Cochrane Database System Review 2003:CD002278.
Mendes FM, Nicolau J. Utilization of laser fluorescence to monitor caries lesions development in primary teeth. J Dent Child (Chic) 2004;71(2):139–142.
Paes Lerne AF, Tabchoury CR, Zero DT, Cury JA. Effect of fluoridated dentifrice and acidulated phosphate fluoride application on early artificial carious lesions. Am J Dent 2003;16(2):91–95.
Santaella MR, Braun A, Matson E, Frentzen M. Effect of diode laser and fluoride varnish on initial surface demineralisation of primary dentition enamel: an in vitro study. Int J Paediatr Dent 2004 14(3):199–203.
Sheiham A. Dietary effects on dental diseases. Public Health Nutr 2001;4:569–591.
Splieth C, Meyer G. Factors for changes of caries prevalence among adolescents in Germany. Eur J Oral Sci 1996;104:444–451.
Ten Cate JM, Duijsters PP. Alternating demineralization and remineralization of artificial enamel lesions. Caries Res 1982;16:201–210.
TenCate JM, Timmer K, Shariati M, Featherstone JD. Effect of timing of fluoride treatment on enamel de- and remineralization in vitro: a pH-cycling study. Caries Res 1988;22(1):20–26.
Thaveesangpanich P, Itthagarun A, King NM, Wefel JS, Tay FR. In vitro model for evaluating the effect of child formula toothpastes on artificial caries in primary dentition enamel. Am J Dent 2005;18(3):212–216.
Toumba KJ, Curzon ME. Fluoride concentration in saliva related to dental caries in primary teeth. Eur J Paed Dent 2001;2:15–19.
Wefel JS. Effects of fluoride on caries development and progression using intraoral models. J Dent Res 1990;69 Spec No: 626-633; discussion 634-626.
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Itthagarun, A., Thaveesangpanich, P., King, N.M. et al. Effects of different amounts of a low fluoride toothpaste on primary enamel lesion progression: a preliminary study using in vitro pH-cycling system. Eur Arch Paediatr Dent 8, 69–73 (2007). https://doi.org/10.1007/BF03262573
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DOI: https://doi.org/10.1007/BF03262573