References
Atkinson RL, Williams FL, Drake CR, Berke LK, Bibbs ML. Naltrexone for weight loss in obesity. Paper presented at the 4th International Congress on Obesity, 1983
Atkinson RL, Berke LK, Drake CR, Bibbs ML, Williams FL, et al. Effects on long-term therapy with naltrexone on body weight in obesity. Clinical Pharmacological Therapy 38: 419–422, 1985
Blumberg H, Dayton HB. Naloxone and related compounds. In Kosterlitz et al. (Eds) Agonist and antagonist actions of narcotic analgesic drugs, pp. 110–119, Macmillan, New York, 1973
Blumberg H, Dayton HB, Wolf PS. Analgesic properties of the narcotic antagonist EN-2234 A. Pharmacologist 10: 201, 1968
Blumberg H, Pachter IJ, Matossian Z. US Patient 3,332,950, 25 July, 1967
Brahen LM, Henderson RK, Capone T, Kordal N. Naltrexone treatment in a jail work-release program. Journal of Clinical Psychiatry 49(2): 42–45, 1984
Brahen LM, Weichert V, Capone T. Narcotic antagonist treatment of the criminal justice patient: institutional vs. outpatient. In Julius et al. (Eds) Narcotic antagonists: naltrexone progress report, National Institute on Drug Abuse Research Monograph Vol. 9, pp. 93–98, US Government Printing Office, Washington DC, 1976
Charney DS, Sternberg DE, Kleber HD, Heninger GR, Redmond Jr DR. The clinical use of clonidine in abrupt withdrawal from methadone. Archives of General Psychiatry 38: 1273–1277, 1981
Crowley TJ, Wagner JE, Zerbe G, MacDonald M. Naltrexone-induced dysphoria in former opioid addicts. American Journal of Psychiatry 142: 1081–1084, 1985
Freedman A, Fink M, Sharoff R, Zaks A. Clinical studies of cyclazocine in the treatment of narcotic addiction. American Journal of Psychiatry 124: 1499–1504, 1968
Ginzburg HM. Use of clonidine or lofexidine to detoxify from methadone maintenance or other opioid dependencies. In Cooper et al. (Eds) Research on the treatment of narcotic addiction: state of the art, pp. 174–211, NIDA Treatment Research Monograph Series, Rockville, Maryland, 1983
Ginzburg HM. Substance substitution: do methadone maintenance patients become alcoholics? In Seixas (Ed.) Currents in alcoholism, Vol. 2, pp. 253–268, Grune & Stratton, New York, 1977
Ginzburg HM. Acquired immunodeficiency syndrome (AIDS) among intravenous drug users. Public Health Reports 99: 206–211, 1984a
Ginzburg HM. Naltrexone: its clinical utility. NIDA Treatment Research Report, Rockville, Maryland, 1984b
Ginzburg HM. Naltrexone: its clinical utility. Advances in Alcohol and Substance Abuse 5: 83–103, 1986
Ginzburg HM, Glass WJ. The role of the National Institute on Drug Abuse in the development of naltrexone. Journal of Clinical Psychiatry 49(2): 4–6, 1984
Gold MS, Pottash AC. The neurobiological implications of clonidine HCl. Annals of the New York Academy of Sciences 362: 191–202, 1981
Gold MS, Redmond DE, Kleber HD. Clonidine in opiate withdrawal. Lancet 1: 929–930, 1978
Gold MS, Dackis CA, Washton AM. The sequential use of clonidine and naltrexone in the treatment of opiate addicts. Advances in Alcohol and Substance Abuse 3: 19–39, 1984
Greenstein RA, Arndt IC, McLellan AT, O’Brien CP, Evans B. Naltrexone: a clinical perspective. Journal of Clinical Psychiatry 49(2): 25–28, 1984
Gritz ER, Shiffman SM, Jarvik ME, Schlesinger J, Charuvastra VC. Naltrexone: physiological and psychological effects of single doses. Clinical Pharmacology and Therapeutics 19: 773–776, 1976
Herman BH, Holtzman SG. Repeated administration of naltrexone and diphenorphine decreases food intake and body weight in squirrel monkeys. Life Sciences 34: 1–12, 1984
Hollister LE, Johnson K, Boukhabza D, Gillespie HK. Aversive effects of naltrexone in subjects not dependent on opiates. Journal of Drug and Alcohol Dependence 8: 37–41, 1981
Hyman BT, Eslinger PJ, Damasio AR. Effect of naltrexone on senile dementia of the Alzheimer type. Journal of Neurology, Neurosurgery, and Psychiatry 48: 1169–1171, 1985
Ionescu F, Klee W, Katz R. Antagonist potency and receptor binding. Life Sciences 16: 1973–1974, 1975
Jaffe JH. Drug addiction and drug abuse. In Gilman AG et al. (Eds) The pharmacological basis of therapeutics, 6th ed., pp. 535–584, Macmillan, New York, 1980
Jaffe JH, Brill L. Cyclazocine, a long-acting narcotic antagonist: its voluntary acceptance as a treatment modality by narcotic abusers. International Journal of the Addictions 1: 99–123, 1966
Jasinski DR, Johnson RE, Kocher TR. Clonidine in morphine withdrawal. Archives of General Psychiatry 42: 1063–1066, 1985
Judson BA, Goldstein A. Symptom complaints of patients maintained on methadone, LAAM (methadyl acetate), and naltrexone at different times in their addiction careers. Journal of Drug and Alcohol Dependence 10: 269–282, 1982
Judson BA, Goldstein A, Inturrisi CE. Naltrexone treatment of heroin addiction: efficacy and safety in a double-blind dosage comparison. Journal of Drug and Alcohol Dependence 7: 325–346, 1981
Judson BA, Himmelberger DU, Goldstein A. The naloxone test for opiate dependence. Clinical Pharmacology and Therapeutics 27: 492–501, 1980
Kleber HD. Naltrexone. Journal of Substance Abuse Treatment 2: 117–120, 1985
Kleber HD, Kosten TR, Gaspari J, Topazian R. Nontolerance to the opioid antagonism of naltrexone. Biological Psychiatry 20: 66–72, 1985
Licko V. Overview of human pharmacokinetics of naltrexone. In Willette et al. (Eds) Naltrexone antagonists: naltrexone pharmacochemistry and sustained-release preparations, National Institute on Drug Abuse Research Monograph, Vol. 28, pp. 161–171, US Government Printing Office, Washington DC, 1981
Ling W, Wesson DR. Naltrexone treatment for addicted healthcare professionals: a collaborative private practice experience. Journal of Clinical Psychiatry 49(2): 46–48, 1984
Lowy MT, Yim GKW. The effect of naltrexone is independent of its suppressant effect on water intake. Neuropharmacology 20: 883–886, 1981
MacDonald MG, Moss IR, Kefale GG, Ginzburg HM, Fink RJ, et al. The effect of naltrexone on apnea of prematurity and on plasma b-endorphin-like immunoreactivity. Developmental Pharmacology and Therapeutic 9: 301–309, 1986
McNicholas LF, Martin WR. New and experimental therapeutic roles for naloxone and related opioid antagonists. Drugs 27: 81–93, 1984
Maggio CA, Presta E, Bracco EF, Vasselli JR, Kissileff HR, et al. Naltrexone and human eating behavior: a dose-ranging inpatient trial in moderately obese men. Brain Research Bulletin 14: 657–661, 1985
Mandenoff AF, Fumeron F, Apfelbaum M, Margules DL. Endogenous opiates and energy balance. Science 215: 1536–1538, 1982
Martin WR, Gorodetzky CW. Demonstration of tolerance to and dependence on N-allylnormorphine (nalorphine). Journal of Pharmacology and Experimental Therapeutics 150: 437–442, 1965
Martin WR, Jasinski DR, Mansky PA. Naltrexone, an antagonist for the treatment of heroin dependence. Archives of General Psychiatry 28: 784–791, 1973
Meyer MC, Straughn AB, Man-Wail P, Schary WL, Whitney CC. Bioequivalence, dose-proportionality, and pharmacokinetics of naltrexone after oral administration. Journal of Clinical Psychiatry 49(2): 15–19, 1984
Mitchell JE, Morley JE, Hatsukami D. A double-blind, placebo-controlled trial of naltrexone in obese males. Paper presented at the Neural and Metabolic Bases of Feeding, Satellite Symposium of the Neuroscience Society Meeting, 1984
National Research Council Committee on Clinical Evaluation of Narcotic Antagonists. Clinical evaluation of naltrexone treatment of opiate dependent individuals. Archives of General Psychiatry 35: 335–340, 1978
Petursson H, Lader MH. Benzodiazepine dependence. British Journal of Addiction 76: 133–145, 1981
Rosenkrantz H. Physiologic and morphologic changes in mice and rats fed naltrexone HCl for 24 months. Journal of Clinical Psychiatry 49(2): 11–14 1984
Senay EC, Dorus W, Goldberg F. Withdrawal from methadone maintenance: rate of withdrawal and expectation. Archives of General Psychiatry 34: 361–367, 1977
Szara SI, Ludford JP (Eds). Benzodiazepines: a review of research results, 1980, National Institute of Drug Abuse Research, Monograph 33, US Government Printing Office, Washington DC, 1982
Tennant FS, Rawson RA, Cohen AJ, Mann A. Clinical experience with naltrexone in suburban opioid addicts. Journal of Clinical Psychiatry 49(2): 42–45, 1984
Verebey K. The clinical pharmacology of naltrexone: pharmacology and pharmacodynamics. In Willette et al. (Eds) Narcotic antagonists: naltrexone pharmacochemistry and sustained-release preparations, National Institute on Drug Abuse Research Monograph 28, pp. 147–158, US Government Printing Office, Washington DC, 1981
Verebey K, Volavka J, Mule SJ. Naltrexone: disposition, metabolism, and effects after acute and chronic dosing. Clinical Pharmacology and Therapeutics 20: 315–328, 1976
Volavka J, Resnick RB. Treatment of accidental naltrexone-induced withdrawal. Correspondence. American Journal of Psychiatry 133: 233, 1976
Washton AM, Resnick RB. Clonidine for outpatient detoxification: outpatient clinical trials. American Journal of Psychiatry 137: 1121–1122, 1980
Washton AM, Pottash AC, Gold MS. Naltrexone in addicted business executives and physicians. Journal of Clinical Psychiatry 49(2): 39–41, 1984
Willette RE, Barnett G (Eds). Narcotic antagonists: naltrexone pharmacochemistry and sustained-release preparations, National Institute on Drug Abuse Research Monograph 28, US Government Printing Office, Washington DC, 1981
Wikler A. Recent progress in research on the neurophysiologic basis of morphine addiction. American Journal of Psychiatry 105: 329–338, 1948
Zaks A, Jones T, Fink M, Freedman AM. Naloxone treatment of opiate dependence. Journal of the American Medical Association 215: 2108–2110, 1971
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Ginzburg, H.M., MacDonald, M.G. The Role of Naltrexone in the Management of Drug Abuse. Drugs 2, 83–92 (1987). https://doi.org/10.1007/BF03260007
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DOI: https://doi.org/10.1007/BF03260007