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Journal of the Iranian Chemical Society

, Volume 8, Supplement 1, pp S135–S140 | Cite as

One-pot synthesis of 3,4-Dihydropyrimidin-2(1H)-ones (thiones) promoted by nano-BF3.SiO2

  • B. F. MirjaliliEmail author
  • A. Bamoniri
  • A. Akbari
Article

Abstract

3,4-Dihydropyrimidin-2(1H)-ones and 3,4-dihydropyrimidin-2(1H)-thione were synthesized under solvent free condition in the presence of nano-silica supported boron trifluoride (nano-BF3.SiO2). The reactions were carried out at 80 °C for 15 min under solvent free condition. This methods have some advantages such as good to excellent yield, mild reaction condition, ease of operation and workup, short reaction time and high product purity.

Keywords

Nano-BF3•SiO2 Biginelli reaction Aldehyde 3,4-Dihydropyrimidin-2(1H)-ones 3,4-Dihydropyrimidin-2(1H)-thiones 

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Copyright information

© Iranian Chemical Society 2011

Authors and Affiliations

  1. 1.Department of Chemistry, College of ScienceYazd UniversityYazdI. R. Iran
  2. 2.Department of Organic Chemistry, Faculty of ChemistryUniversity of KashanKashanI.R. Iran

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