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PEG-SO3H as a new, highly efficient and homogeneous polymeric catalyst for the synthesis of bis(indolyl)methanes and 4,4′-(arylmethylene)-bis(3-methyl-1-phenyl-1Hpyrazol-5-ol)s in water

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Abstract

In this work, a green, simple and highly efficient procedure for the synthesis of bis(indolyl)methanes and 4,4′- (arylmethylene)-bis(3-methyl-1-phenyl-1H-pyrazol-5-ol)s [as an important class of bis(pyrazolyl)methanes] is described. The condensation of indoles or 1-phenyl-3-methylpyrazol-5-one with carbonyl compounds catalyzed by poly(ethylene glycol)-bound sulfonic acid (PEG-SO3H) in water affords the title compounds in high yields and relatively short reaction times.

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Authors and Affiliations

  1. Department of Chemistry, Faculty of Sciences, Persian Gulf University, Bushehr, 75169, Iran

    A. Hasaninejad, M. Shekouhy, S. M. S. Hoseini Ghattali & N. Golzar

  2. Department of Chemistry, Payame Noor University (PNU), Iran

    A. Zare

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  1. A. Hasaninejad
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  2. M. Shekouhy
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  3. A. Zare
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  4. S. M. S. Hoseini Ghattali
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Correspondence to A. Hasaninejad or A. Zare.

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Hasaninejad, A., Shekouhy, M., Zare, A. et al. PEG-SO3H as a new, highly efficient and homogeneous polymeric catalyst for the synthesis of bis(indolyl)methanes and 4,4′-(arylmethylene)-bis(3-methyl-1-phenyl-1Hpyrazol-5-ol)s in water. JICS 8, 411–423 (2011). https://doi.org/10.1007/BF03249075

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