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Organotin(IV) complexes of 4-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)benzoic acid: Synthesis, spectral characterization and biological applications

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Abstract

4-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)benzoic acid and its complexes with methyl-, n-butyl-, phenyl-, benzyl- and octyl-tin have been synthesized and characterized by elemental analysis and spectral studies. The geometry around the tin atom has been deduced from both solid and solution studies. These complexes were also tested against different bacteria and fungi to determine their toxicity. LD50 data was also calculated using the Brine Shrimp method.

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Authors and Affiliations

  1. Department of Chemistry, Quaid-i-Azam University, 45320, Islamabad, Pakistan

    K. Shahid, S. Shahzadi & S. Ali

  2. Department of Chemistry, Allama Iqbal Open University, H-8, Islamabad, Pakistan

    M. H. Bhatti

  3. H.E.J. Research Institute of Chemistry, University of Karachi, Karachi, Pakistan

    K. M. Khan

Authors
  1. K. Shahid
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  2. S. Shahzadi
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  3. S. Ali
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  4. M. H. Bhatti
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  5. K. M. Khan
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Correspondence to S. Ali.

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Shahid, K., Shahzadi, S., Ali, S. et al. Organotin(IV) complexes of 4-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)benzoic acid: Synthesis, spectral characterization and biological applications. JICS 2, 140–148 (2005). https://doi.org/10.1007/BF03247205

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  • DOI: https://doi.org/10.1007/BF03247205

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