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Quaternary ammonium salts as highly efficient and green alkylating agents for N-alkylation of azaheterocycles under microwave irradiation

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Abstract

An efficient, simple and green procedure for N-alkylation of azaheterocycles by quaternary ammonium salts in the presence of K2CO3 under microwave irradiation is described. Using this method, N-alkyl derivatives of azaheterocycles are obtained in good to excellent yields and short reaction times.

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Authors and Affiliations

  1. Department of Chemistry, College of Sciences, Shiraz University, Shiraz, 71454, Iran

    A. Khalafi-Nezhad, A. Parhami & A. R. Moosavi Zare

  2. Department of Chemistry, College of Sciences, Payame Noor University (PNU), Iran

    A. Zare

  3. Department of Chemistry, Faculty of Sciences, Persian Gulf University, Bushehr, 75169, Iran

    A. Hasaninejad

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  1. A. Khalafi-Nezhad
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  2. A. Zare
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  3. A. Parhami
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  4. A. Hasaninejad
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  5. A. R. Moosavi Zare
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Correspondence to A. Khalafi-Nezhad.

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This paper is dedicated to Professor Habib Firouzabadi on the occasion of his retirement for his great efforts and contribution in the field of organic chemistry

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Khalafi-Nezhad, A., Zare, A., Parhami, A. et al. Quaternary ammonium salts as highly efficient and green alkylating agents for N-alkylation of azaheterocycles under microwave irradiation. JICS 5 (Suppl 1), S40–S46 (2008). https://doi.org/10.1007/BF03246487

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  • DOI: https://doi.org/10.1007/BF03246487

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