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Boric acid catalyzed efficient synthesis of symmetrical N,N′-alkylidene bisamides

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Abstract

Symmetrical N,N′-alkylidene bisamides were synthesized in excellent yield by condensation of aromatic aldehydes and amides in the presence of boric acid as a catalyst under thermal and neat microwave irradiation conditions. It is the first successful report of boric acid has been used as Lewis acid catalyst for the preparation of symmetrical N,N′-alkylidene bisamides. The remarkable advantages offered by this method are green catalyst, mild reaction condition, simple procedure, fast reaction and moderate to good yield of products.

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Authors and Affiliations

  1. Department of Polymer Science, University of Madras, Guindy Campus, Chennai, 600 025, India

    G. Harichandran & S. David Amalraj

  2. Organic Chemistry Laboratory, Central Leather Research Institute, Adyar, Chennai, 600 020, India

    P. Shanmugam

Authors
  1. G. Harichandran
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  2. S. David Amalraj
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  3. P. Shanmugam
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Correspondence to G. Harichandran or P. Shanmugam.

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Harichandran, G., Amalraj, S.D. & Shanmugam, P. Boric acid catalyzed efficient synthesis of symmetrical N,N′-alkylidene bisamides. JICS 8, 298–305 (2011). https://doi.org/10.1007/BF03246228

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  • DOI: https://doi.org/10.1007/BF03246228

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