Skip to main content
Log in

Voltammetric determination of vitamin B6 (Pyridoxine) using multi wall carbon nanotube modified carbon-ceramic electrode

  • Published:
Journal of the Iranian Chemical Society Aims and scope Submit manuscript

Abstract

A simple procedure was developed to prepare a carbon-ceramic electrode (CCE) modified with multi wall carbon nanotube (MWCNT). The electrochemical behavior of pyridoxine was investigated on the obtained electrode in phosphate buffer solution (PBS), pH 7.0. During oxidation of pyridoxine on the MWCNT/CCE, one irreversible anodic peak at Ep = 716 mV vs. SCE appeared. Cyclic voltammetric study indicated that the oxidation process is irreversible and diffusion controlled. The number of exchanged electrons in the electro-oxidation process was obtained, and the data indicated that pyridoxine is oxidized via two one-electron steps. The results revealed that MWCNT promotes the rate of oxidation by increasing the peak current, so that pyridoxine is oxidized at lower potentials, which thermodynamically is more favorable compared with on the bare CCE. A sensitive, simple and time-saving differential pulse voltammetric procedure was developed for the analysis of pyridoxine. Using the proposed method, pyridoxine can be determined with a detection limit of 95 nM. The applicability of the method to direct assays of some commercial pharmaceutical samples is described.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  1. A.E. Martell, Acc. Chem. Res. 22 (1989) 115.

    CAS  Google Scholar 

  2. A.A. Alwarthan, F.A. Aly, Talanta 45 (1998) 1131.

    CAS  Google Scholar 

  3. R. Jiménez-Prieto, M. Silva, D. Pérez-Bendito, Talanta 44 (1997) 1463.

    Google Scholar 

  4. J.L.F.C. Lima, M.C.B.S.M. Montenegro, A.M.R. Silva, J. Pharm. Biomed. Anal. 9 (1991) 1041.

    CAS  Google Scholar 

  5. C. Cimpoiu, A. Hosu, J. Liq. Chromatogr. Related Technol. 30 (2007) 701.

    CAS  Google Scholar 

  6. W. Hou, H. Ji, E. Wang, Anal. Chim. Acta 230 (1990) 207.

    CAS  Google Scholar 

  7. J. Yang, R. Han, B. Su, C. Lin, N. Wang, J. Hu, Anal. Sci. 14 (1998) 965.

    CAS  Google Scholar 

  8. R.D. Bautista, A.I. Jiménez, F. Jiménez, J.J. Arias, J. Pharm. Biomed. Anal. 15 (1996) 183.

    CAS  Google Scholar 

  9. S.O. Algar, N.R. Martos, A.M. Díaz, Spectrosc. Lett. 36 (2003) 133.

    CAS  Google Scholar 

  10. M.H. Hashmi, M.U.H. Hashmi, Assay of vitamins in pharmaceutical preparations, John Wiley & Sons, London, 1973.

    Google Scholar 

  11. P. Söderhjelm, J. Lindquist, Analyst 100 (1975) 349.

    Google Scholar 

  12. Q. Hu, T. Zhou, L. Zhang, H. Li, Y. Fang, Anal. Chim. Acta 437 (2001) 123.

    CAS  Google Scholar 

  13. G. Chen, X. Ding, Z. Cao, J. Ye, Anal. Chim. Acta 408 (2000) 249.

    CAS  Google Scholar 

  14. M.F.S. Teixeira, A. Segnini, F.C. Moraes, L.H. Marcolino-Júnior, O. Fatibello-Filho, E.T.G. Cavalheiro, J. Brazil. Chem. Soc. 14 (2003) 316.

    CAS  Google Scholar 

  15. M.F.S. Teixeira, G. Marino, E.R. Dockal, E.T.G. Cavalheiro, Anal. Chim. Acta 508 (2004) 79.

    CAS  Google Scholar 

  16. W. Qu, K. Wu, S. Hu, J. Pharm. Biomed. Anal. 36 (2004) 631.

    CAS  Google Scholar 

  17. L. Tan, Q. Xie, S. Yao, Electroanalysis 16 (2004) 1592.

    CAS  Google Scholar 

  18. M.H. Pournaghi-Azar, H. Dastangoo, M. Ziaei, J. Solid State Electrochem. 11 (2007) 1221.

    CAS  Google Scholar 

  19. P.B. Desai, R.M. Kotkar, A.K. Srivastava, J. Solid State Electrochem. 12 (2008) 1067.

    CAS  Google Scholar 

  20. L. Agüí, P. Yáñez-Sedeño, J.M. Pingarrón, Anal. Chim. Acta 622 (2008) 11.

    Google Scholar 

  21. M. Tsionsky, G. Gun, V. Glezer, O. Lev, Anal. Chem. 66 (1994) 1747.

    CAS  Google Scholar 

  22. O. Lev, Z. Wu, S. Bharathi, V. Glezer, A. Modestov, J. Gun, L. Rabinovich, S. Sampath, Chem. Mater. 9 (1997) 2354.

    CAS  Google Scholar 

  23. V.G. Gavalas, R. Andrews, D. Bhattacharyya, L.G. Bachas, Nano. Lett. 1 (2001) 719.

    CAS  Google Scholar 

  24. A.J. Bard, L.R. Faulkner, Electrochemical methods; fundamentals and applications. Wiley, New York, 2004, p 103, 236.

    Google Scholar 

  25. M.L. Wang, Y.Y. Zhang, Q.J. Xie, S.Z. Yao, Electrochim. Acta 51 (2005) 1059.

    CAS  Google Scholar 

  26. E. Jacobsen, T.M. Tommelstad, Anal. Chim. Acta 162 (1984) 379.

    CAS  Google Scholar 

  27. P. Söderhjelm, J. Lindquist, Acta Pharm. Suec. 13 (1976) 201.

    Google Scholar 

  28. Y. Wu, F. Song, Bull. Korean Chem. Soc. 29 (2008) 38.

    CAS  Google Scholar 

  29. J.-M. Zen, J.-C. Chen, A.S. Kumar, Tamkang J. Sci. Eng. 5 (2002) 219.

    Google Scholar 

  30. S.M. Cottica, J. Nozaki, H.S. Nakatani, C.C. Oliveira, N.E. de Souza, J.V. Visentainer, J. Braz. Chem. Soc. 20 (2009) 496.

    CAS  Google Scholar 

  31. D.D. Perrin, Dissociation Constants of Organic Bases in Aqueous Solution, Butterworths, London, 1972.

    Google Scholar 

  32. J.A. Dean Lange’s Handbook of Chemistry, 13th ed., McGraw-Hill, New York, 1985, pp 5–39.

    Google Scholar 

  33. Windholz, M.; Budavari, S.; Stroumtsos, L. Y.; Fertig, M. N.; The Merck Index, 9th ed., Merck & CO: EUA, 1976.

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to B. Habibi.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Habibi, B., Phezhhan, H. & Pournaghi-Azar, M.H. Voltammetric determination of vitamin B6 (Pyridoxine) using multi wall carbon nanotube modified carbon-ceramic electrode. JICS 7 (Suppl 2), S103–S112 (2010). https://doi.org/10.1007/BF03246189

Download citation

  • Received:

  • Accepted:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF03246189

Keywords

Navigation