Macromolecular Research

, Volume 16, Issue 3, pp 231–237

Effect of composition and synthetic route on the microstructure of biodegradable diblock copolymer, poly(ε-caprolactone-co-L-lactide)-b-poly(ethylene glycol)

  • Younjin Min
  • Seongnam Lee
  • Jung-Ki Park
  • Kuk Young Cho
  • Shi-Joon Sung
Article

DOI: 10.1007/BF03218858

Cite this article as:
Min, Y., Lee, S., Park, JK. et al. Macromol. Res. (2008) 16: 231. doi:10.1007/BF03218858

Abstract

Biodegradable poly(ε-caprolactone-co-L-lactide)-b-poly(ethylene glycol) (PCLA-b-PEG) copolymers were synthesized via solution polymerization by varying the feed composition of ε-caprolactone (ε-CL) and L-lactide (LLA) (ε-CL: LLA=10∶0, 7∶3, 5∶5, 3∶7, 0∶10). The feed ratio based on weight is in accordance with the copolymer composition except for the case of ε-CL: LLA=3:7 (C3L7), which was verified by1H-NMR. Two different approaches were used for the exceptional case, which is an extension of the reaction time or the sequential introduction of the monomer. A copolymer composition of ε-CL: LLA=3:7 could be obtained in either case. The chemical microstructure of PCLA-b-PEG was determined using the13C-NMR spectra and the effect of the sequential structure on the thermal properties and crystallinity were examined. Despite the same composition ratio of the copolymer, the microstructure can differ according to the reaction conditions.

Keywords

biodegradable copolymer microstructure PEG sequence distribution 

Copyright information

© The Polymer Society of Korea and Springer 2008

Authors and Affiliations

  • Younjin Min
    • 1
  • Seongnam Lee
    • 1
  • Jung-Ki Park
    • 1
  • Kuk Young Cho
    • 2
  • Shi-Joon Sung
    • 3
  1. 1.Department of Chemical & Biomolecular EngineeringKorea Advanced Institute of Science and TechnologyDaejeonKorea
  2. 2.Division of Advanced Materials EngineeringKongju National UniversityChungnamKorea
  3. 3.Display and Nano Devices LaboratoryDaegu Gyeongbuk Institute of Science and TechnologyDaeguKorea

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