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Effect of composition and synthetic route on the microstructure of biodegradable diblock copolymer, poly(ε-caprolactone-co-L-lactide)-b-poly(ethylene glycol)

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Abstract

Biodegradable poly(ε-caprolactone-co-L-lactide)-b-poly(ethylene glycol) (PCLA-b-PEG) copolymers were synthesized via solution polymerization by varying the feed composition of ε-caprolactone (ε-CL) and L-lactide (LLA) (ε-CL: LLA=10∶0, 7∶3, 5∶5, 3∶7, 0∶10). The feed ratio based on weight is in accordance with the copolymer composition except for the case of ε-CL: LLA=3:7 (C3L7), which was verified by1H-NMR. Two different approaches were used for the exceptional case, which is an extension of the reaction time or the sequential introduction of the monomer. A copolymer composition of ε-CL: LLA=3:7 could be obtained in either case. The chemical microstructure of PCLA-b-PEG was determined using the13C-NMR spectra and the effect of the sequential structure on the thermal properties and crystallinity were examined. Despite the same composition ratio of the copolymer, the microstructure can differ according to the reaction conditions.

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Authors and Affiliations

  1. Department of Chemical & Biomolecular Engineering, Korea Advanced Institute of Science and Technology, 305-701, Daejeon, Korea

    Younjin Min, Seongnam Lee & Jung-Ki Park

  2. Division of Advanced Materials Engineering, Kongju National University, 303-717, Chungnam, Korea

    Kuk Young Cho

  3. Display and Nano Devices Laboratory, Daegu Gyeongbuk Institute of Science and Technology, 704-230, Daegu, Korea

    Shi-Joon Sung

Authors
  1. Younjin Min
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  2. Seongnam Lee
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  3. Jung-Ki Park
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  4. Kuk Young Cho
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  5. Shi-Joon Sung
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Correspondence to Kuk Young Cho.

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Min, Y., Lee, S., Park, JK. et al. Effect of composition and synthetic route on the microstructure of biodegradable diblock copolymer, poly(ε-caprolactone-co-L-lactide)-b-poly(ethylene glycol). Macromol. Res. 16, 231–237 (2008). https://doi.org/10.1007/BF03218858

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  • DOI: https://doi.org/10.1007/BF03218858

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