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Synthesis and microphase separation of biodegradable poly(ε-caprolactone)-poly(ethylene glycol)-poly(ε-caprolactone) multiblock copolymer films

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Abstract

Poly(ε-caprolactone)-poly(ethylene glycol)-poly(ε-caprolactone) (PCL-PEG-PCL) multiblock copolymers at various hydrophobic-hydrophilic ratios were successfully synthesized by the chain extension of triblock copolymers through isocyanate (hexamethylene diisocyanate). Biodegradable films were prepared from the resulting multiblock copolymers using the casting method. The mechanical properties of the films were improved by chain extension of the triblock copolymers, whereas the films prepared by the triblock copolymers were weak and brittle. Atomic force microscopy (AFM) of the multiblock copolymer film showed that the hydrophilic PEG had segregated on the film surface. This is consistent with the observed contact angle of the films.

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Authors and Affiliations

  1. Nanosphere Process and Technology Laboratory, Department of Chemical Engineering, Yonsei University, 120-749, Seoul, Korea

    Jae Ho You, Sung-Wook Choi & Jung-Hyun Kim

  2. Department of Thoracic and Cardiovascular Surgery, East-West Neo Medical Center, College of Medicine, Kyung Hee University, 130-701, Seoul, Korea

    Young Tae Kwak

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  1. Jae Ho You
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  2. Sung-Wook Choi
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  3. Jung-Hyun Kim
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  4. Young Tae Kwak
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Correspondence to Jung-Hyun Kim.

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You, J.H., Choi, SW., Kim, JH. et al. Synthesis and microphase separation of biodegradable poly(ε-caprolactone)-poly(ethylene glycol)-poly(ε-caprolactone) multiblock copolymer films. Macromol. Res. 16, 609–613 (2008). https://doi.org/10.1007/BF03218568

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  • DOI: https://doi.org/10.1007/BF03218568

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