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Association between white blood cell and red blood cell counts within reference range and metabolic syndrome in Korean men and women

Toxicology and Environmental Health Sciences volume 2, pages 238–244 (2010)Cite this article

Abstract

The aim of the present study was to assess the relationship between white blood cell (WBC) or red blood cell (RBC) counts, and metabolic syndrome (MS). We analyzed 5,178 subjects ≥20 yr of age, who participated in the 2005 Korean National Health and Nutrition Examination Survey. Each multivariate adjusted mean of WBC and RBC was significantly higher in subjects with MS components than the control group, respectively, with the exception for men with hyperglycemia and women with lower values of high-density lipoprotein (HDL) cholesterol. WBC and RBC counts were correlated with MS components. In multivariate logistic regression analysis, the highest quartile of WBC or RBC counts were presented with 1.5- or 2.5-fold increases in the risk of MS, respectively, compared to the lowest quartile groups. These findings demonstrated that increased WBC or RBC counts within the reference range could associated with various MS components and the risk of MS in the Korean population.

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Authors and Affiliations

  1. Department of Family Medicine, Yonsei University Wonju College of Medicine, Wonju, Korea

    Jong-Koo Kim

  2. Department of Family Medicine, Yonsei University College of Medicine, Seoul, Korea

    Yong-Jae Lee, Ji-Won Lee, Jae-Yong Shim, Duk-Chul Lee & Hye-Ree Lee

  3. Department of Health Promotion Center, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul, Korea

    Jung-Hyun Lee

  4. Department of Nursing, Mokpo National University, Muan, Jeonnam, Korea

    Aeyong Eom

  5. Department of Preventive Medicine, Institute of Genomic Cohort, Institute of Life-Long Health and Institute of Occupational Medicine, Yonsei University Wonju College of Medicine, Korea

    Sang-Baek Koh

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  1. Jong-Koo Kim
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  2. Yong-Jae Lee
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  9. Sang-Baek Koh
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Correspondence to Hye-Ree Lee or Sang-Baek Koh.

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Kim, JK., Lee, YJ., Lee, JW. et al. Association between white blood cell and red blood cell counts within reference range and metabolic syndrome in Korean men and women. Toxicol. Environ. Health. Sci. 2, 238–244 (2010). https://doi.org/10.1007/BF03217489

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  • DOI: https://doi.org/10.1007/BF03217489

Keywords

  • White blood cell count
  • Red blood cell count
  • Inflammation
  • Insulin resistance
  • Metabolic syndrome