Abstract
In this paper, we discuss the performances of gold nanosensors based on Localized Surface Plasmon Resonance (LSPR) designed by Electron Beam Lithography (EBL) in the context of biological and chemical sensing. We demonstrate the sensitivity of our gold nanosensors by studying the influence of the concentration of 11-mercaptoundecanoic acid (MUA) on the shift of LSPR wavelength. Additionally, to study the selectivity of our nanosensors, the system Biotin/Streptavidin was used to detect very weak concentration of biomolecules. These results represent new steps for applications in chemical research and medical diagnostics.
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Grégory Barbillon completed his PhD in Physics (2007) at the University of Technology of Troyes under the supervision of Prof. J.-L. Bijeon. Then he was awarded a post-doc position at the University of Lyon. In recent years, his interest were focused on plasmonics, the fabrication and the study of biological and chemical nanosensors based on localized surface plasmon resonance, the scanning near-field optical microscopy and the luminescence of nanoparticles.
Jean-Louis Bijeon is associate professor at University of Technology of Troyes, he is the Head of the Physics, Materials and Nanotechnology department. He got his PhD from University of Burgundy (France) and from Oak Ridge National Laboratory (USA) in 1989 on Surface Enhanced Raman Scattering and its relations with the Localized Surface Plasmon Resonance on submicronic metallic particles. He was the R&D project manager, in scanning tunnelling microscopy and photon scanning tunnelling microscopy at SPIRAL R&D a French private company, from January 1990 to February 1994. Now its research themes inside the Nanotechnology and Optical Instrumentation Laboratory at UTT, are near-field optics and related fields involving surface plasmon resonance in metallic nanoparticles, and plasmonics. Another field of its activities is the expertise in atomic force microscopy.
Jérôme Plain gratuated in Physics (1998) and completed his PhD (europeus doctor) in Physics (2001) at the Université of Poitiers and the Autonomous University of Barcelona. He is now assistant professor of physics at the University of Technology of Troyes. In recent years, his interests were mainly focused on metal nanostructures and their applications.
Marc Lamy de la Chapelle got is PhD in 1998 on the Raman spectroscopy of carbon nanotubes. Since 2001, he was assistant professor at the University of Technology of Troyes. He is specialized in the vibrational spectroscopies and more especially on the Surface Enhanced Raman Scattering. He was recently promoted Professor at the University of Paris 13 working on the application of SERS to the characterisation of biological structures.
Pierre-Michel Adam has obtained his PhD thesis in January 95 at the University of Burgundy (France). In january 95, Pierre Michel Adam has joined the University of Technology of Troyes as an assistant professor and has been appointed professor since february 2003. His fields of research are near-field microscopy and spectroscopy (fluorescence, absorption), surface plasmons, surface enhanced Raman scattering.
Pascal Royer is a full Professor in Physics at the University of Technology of Troyes (UTT). He has a background in physics and particularly in optics/ optoelectronics, graduated in Dijon (PhD) and Grenoble (HDR). He is the Director of the Nanotechnology and Optical Instrumentation Laboratory he founded at UTT in 1994. These scientific investigations concern the study of physical/chemical properties of nanostructures by near field optical microscopy and spectroscopy so as the development of related instrumentation and the understanding of physical phenomena involved at this scale. He has also always been involved in plasmonics.
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Barbillon, G., Bijeon, JL., Plain, J. et al. Biological and chemical gold nanosensors based on localized surface plasmon resonance. Gold Bull 40, 240–244 (2007). https://doi.org/10.1007/BF03215587
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DOI: https://doi.org/10.1007/BF03215587