Gold Bulletin

, Volume 40, Issue 3, pp 213–218 | Cite as

Protein binding to gold colloids

  • Ossi Horovitz
  • Gheorghe Tomoaia
  • Aurora Mocanu
  • Traianos Yupsanis
  • Maria Tomoaia-Cotisel
Open Access
Gold 2006 Scientific Papers


Gold nanoparticles (size from 10 to 50 nm) were synthesized by three different methods and were characterized by UV-Vis spectroscopy and transmission electron microscopy (TEM). The shape and size distribution of gold nanoparticles were determined. The interaction of major storage protein extracted and purified from aleurone cells of barley with the gold colloids has been examined using absorption UV-Vis spectroscopy and TEM observations. These investigations evidence the binding of aleurone protein to gold nanoparticles. This binding might occur by electrostatic forces between the negatively charged citrate capped gold particles and the positively charged groups of the protein (e.g., arginine and lysine residues).


Gold NANOPARTICLES Gold Particle Gold Colloid TRISODIUM Citrate Gold Sample 
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Copyright information

© World Gold Council 2007

Authors and Affiliations

  • Ossi Horovitz
    • 1
  • Gheorghe Tomoaia
    • 2
  • Aurora Mocanu
    • 1
  • Traianos Yupsanis
    • 3
  • Maria Tomoaia-Cotisel
    • 1
  1. 1.Faculty of Chemistry and Chemical Engineering“Babes-Bolyai” University of Cluj-NapocaCluj-NapocaRomania
  2. 2.Department of Orthopedic Surgery“Iuliu Hatieganu” University of Medicine and PharmacyCluj-NapocaRomania
  3. 3.School of Chemistry, Laboratory of BiochemistryAristotelian UniversityThessalonikiGreece

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