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Isolated central nervous system histoplasmosis in an immunocompetent patient: 53-month hiatus to diagnosis and treatment

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Abstract

Chronic meningitis may result from a wide range of etiologies, both infectious and noninfectious, and is often diagnostically challenging. In most series, tuberculosis remains the most common recognized cause. Of the fungal diseases resulting in chronic meningitis,Cryptococcus is the most common. When untreated, the infectious meningitides typically exhibit an inexorably progressive course with high morbidity and mortality. We report a patient with chronic meningitis due toHistoplasma capsulatum who exhibited a remarkably benign course despite being untreated for the disorder for more than 4 years.

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Authors and Affiliations

  1. Department of Neurology, University of Kentucky College of Medicine, Kentucky Clinic Room L-445, 740 S. Limestone Street, 40536-0281, Lexington, KY, USA

    Joseph R Berger

  2. Departments Internal Medicine, University of Kentucky College of Medicine, Lexington, Kentucky, USA

    Joseph R Berger & Richard N Greenberg

  3. Lexington VA Medical Center, Lexington, Kentucky, USA

    Richard N Greenberg

Authors
  1. Joseph R Berger
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  2. Richard N Greenberg
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Correspondence to Joseph R Berger.

Additional information

This paper was first published online on Early Online on 9 November 2010.

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Berger, J.R., Greenberg, R.N. Isolated central nervous system histoplasmosis in an immunocompetent patient: 53-month hiatus to diagnosis and treatment. Journal of NeuroVirology 16, 472–474 (2010). https://doi.org/10.1007/BF03210853

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  • DOI: https://doi.org/10.1007/BF03210853

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