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Identification of chlamydosporol, a mycotoxin isolated from a culture of fusarium tricinctum

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Abstract

Fusarium tricinctum strain (KF 260) isolated from wheat in Poland, produced on maize cultures a compound (C11H14O5, MW226) toxic toArtemia salina. The compound, identified by various spectroscopical tecniques as 5-hydroxy-4-methoxy-6,8a-dimethyl-6, 7-dihydro-2H, 8aH-pyrano/2, 3-b/pyran-2-one, was identical to chlamydosporol, a mycotoxin recentlydiscovered in cultures ofF._ chlamydosporum isolated from rice. The compound showed inhibitory effect on human lymphocyte proliferation at concentration of 25 μg/mL. LD50 onA. salina was 56 μg/mL.

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Authors and Affiliations

  1. Istituto Tossine e Micotossine da Parassiti Vegetali, C.N.R., Via Amendola 197/F, 70126, Bari, Italy

    Michele Solfrizzo & Angelo Visconti

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  1. Michele Solfrizzo
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  2. Angelo Visconti
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Solfrizzo, M., Visconti, A. Identification of chlamydosporol, a mycotoxin isolated from a culture of fusarium tricinctum. Mycotox Res 7 (Suppl 1), 2–7 (1991). https://doi.org/10.1007/BF03192176

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  • DOI: https://doi.org/10.1007/BF03192176

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