Summary
The metabolism of the antiepileptic drug ethosuximide (3-ethyl-3-methylpyrollidine-2,5-dione) (I) in animals and humans is reviewed. Chiral aspects of the metabolism of ethosuximide are discussed. Clarification of the precise nature of the hydroxymetabolites of ethosuximide is presented.
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Millership, J.S., Mifsud, J. & Collier, P.S. The metabolism of ethosuximide. European Journal of Drug Metabolism and Pharmacokinetics 18, 349–353 (1993). https://doi.org/10.1007/BF03190184
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DOI: https://doi.org/10.1007/BF03190184