Summary
Microcomputers have been used in pharmacokinetics for several years, but their use in the area of formulation is a new application.
By using appropriate data on the drug, the dosage form required and its mechanism of absorption and clearance, microcomputers can systematize and speed-up formulation, simplify manufacturing processes and, through simulated models and plasma level predictions, reduce the number of bioavailability studies needed.
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Plenary lecture at the 3rd International Symposium on Biopharmaceutics and Pharmacokinetics, 1982, Strebske Plezo, Czechoslovakia.
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Aiache, J.M., Turlier, M. & Tanguy, A. Pharmacokinetic data processed by microcomputer for the formulation of optimal drug dosage form. European Journal of Drug Metabolism and Pharmacokinetics 9, 89–102 (1984). https://doi.org/10.1007/BF03189611
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DOI: https://doi.org/10.1007/BF03189611