Summary
Trithiozine capsules (1 g) were taken orally by four normal volunteers. Within the first hour after ingestion detectable levels appeared in the plasma; peaks were reached between 2 and 4 hours (7 ug/ml), and 48 hours after administration the levels were still measurable (0.6 ug/ml). Total urinary escretion of trithiozine was between 0.34–0.73% of the administered dose.
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Farina, P., Tognoni, G. & Cornelli, U. Pharmacokinetic profile of trithiozine, a new antisecretory drug, in man. European Journal of Drug Metabolism and Pharmacokinetics 2, 97–100 (1977). https://doi.org/10.1007/BF03189290
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DOI: https://doi.org/10.1007/BF03189290