Total synthesis ofdl-9(11)-dehydrotestosterone anddl-testosterone

  • D K Banerjee
  • K M Damodaran
  • P S N Murthy
  • V Paul
Organic

Abstract

17β-Hydroxy-des-A-androst-9-en-5-one (II, R=OH), prepared fromtrans-1β-hydroxy-8-methyl-4, 5-(3′-methyl-4′-methoxybenzo)-hydrindane (I, R=CH3)′, has been converted intodl-9(II)-dehydrotestosterone (IV, R=OH) anddl-testosterone (IX) in very short sequences of steps, albeit in poor yields.

Keywords

Synthesis steroids ring A formation 

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Copyright information

© Indian Academy of Sciences 1978

Authors and Affiliations

  • D K Banerjee
    • 1
  • K M Damodaran
    • 1
  • P S N Murthy
    • 1
  • V Paul
    • 1
  1. 1.Department of Organic ChemistryIndian Institute of ScienceBangalore

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