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Implantation delay and nidation by progesterone in carrot seed (Daucus carota) extract treated albino rats


In the present study the effect of petroleum ether extract of carrot seeds and progesterone on implantation have been investigated. 0·6 ml/100 g body weight of carrot seed extract was administered subcutaneously from days 1–7 of pregnancy and laparatomized on day 8. No implantation sites were observed. Thereafter graded doses of progesterone 2, 4 or 8 mg/100 g body weight was administered upto day 15 and autopsied on day 16. Two mg of progesterone did not show any effect. However, 4 mg of progesterone treated rats had smaller implantation sites compared to the controls whereas, 8 mg of progesterone was most effective with the result that in almost all the rats, delayed implantation was observed.

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Correspondence to B B Kaliwal.

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Kaliwal, B.B., Ahamed, R.N. & Rao, M.A. Implantation delay and nidation by progesterone in carrot seed (Daucus carota) extract treated albino rats. Proc. Indian Acad. Sci. (Anim. Sci.) 95, 263–268 (1986).

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  • Implantation
  • carrot seed extract
  • progesterone
  • albino rats