Refractory priapism associated with ingestion of yohimbe extract

Abstract

Extracts of the bark of the central African treePausinystalia yohimbe contain yohimbine, an indole alkaloid, which is used to treat erectile dysfunction. The reported side effects of over-the-counter preparations of yohimbine include gastrointestinal upset, anxiety, increased blood pressure, headache, agitation, rash, tachycardia, and frequent urination. In this report, we describe a severe case of intractable priapism associated with the ingestion of yohimbe extract. Management required insertion of a proximal cavernosal spongiosum shunt (Quackles shunt) in the operating room.

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Correspondence to Fermin Barrueto MD.

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Notes: There was no outside funding of any kind used for this study

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Myers, A., Barrueto, F. Refractory priapism associated with ingestion of yohimbe extract. J. Med. Toxicol. 5, 223 (2009). https://doi.org/10.1007/BF03178272

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Keywords

  • yohimbe
  • priapism
  • erectile dysfunction