Extracts of the bark of the central African treePausinystalia yohimbe contain yohimbine, an indole alkaloid, which is used to treat erectile dysfunction. The reported side effects of over-the-counter preparations of yohimbine include gastrointestinal upset, anxiety, increased blood pressure, headache, agitation, rash, tachycardia, and frequent urination. In this report, we describe a severe case of intractable priapism associated with the ingestion of yohimbe extract. Management required insertion of a proximal cavernosal spongiosum shunt (Quackles shunt) in the operating room.
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Notes: There was no outside funding of any kind used for this study
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Myers, A., Barrueto, F. Refractory priapism associated with ingestion of yohimbe extract. J. Med. Toxicol. 5, 223 (2009). https://doi.org/10.1007/BF03178272
- erectile dysfunction