Skip to main content
SpringerLink
Log in

Nuclear oxidation in flavones and related compounds

Part XX. Oxidation of gossypetin to 6∶8-dihydroxy quercetin

  • Published:
Proceedings of the Indian Academy of Sciences - Section A Aims and scope Submit manuscript

Summary

The two stage process of ortho-oxidation is applied to partial methyl ethers of gossypetin in order to introduce a new hydroxyl in the 6 position. The pentamethyl ether with a free hydroxyl in the 7- position does not react with hexamine. On the other hand, its isomer with a free 5-hydroxyl yields a mixture of products, one of which is the 6-aldehyde which could be oxidised by means of hydrogen peroxide. A more satisfactory procedure is to use the tetramethyl ether having the 5 and 8 hydroxyls free. It yields only the 6-aldehyde and subsequent oxidation with hydrogen peroxide leads to the formation of 5∶6∶8-trihydroxy compound. The products are useful partial methyl ethers and yield 6∶8-dihydroxy-quercetin on demethylation and its heptamethyl ether on methylation.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  1. Rao and SeshadriProc. Ind. Acad. Sci.,A, 1947,26, 18.

    Google Scholar 

  2. Row, Seshadri and ThiruvengadamIbid., 1947,26, 18. Rao and SeshadriIbid. Proc. Ind. Acad. Sci.,A, 1948,28, 210.

    Google Scholar 

  3. Seshadri and VenkateswarluIbid., 1946,23, 192. Murti, Row and SeshadriIbid. Proc. Ind. Acad. Sci.,A, 1946,24, 233. Sastri and SeshadriIbid. Proc. Ind. Acad. Sci.,A, 1946,24, 238.

    Google Scholar 

  4. Baker, Nodzu and RobinsonJ.C.S., 1929, 74.

  5. Rao, Rao and SeshadriProc. Ind. Acad. Sci., A., 1944,19, 88.

    Google Scholar 

  6. Rangaswami and SeshadriIbid., 1939,9, 1, and 526; 1941,14, 547.

    Google Scholar 

  7. Rao and SeshadriIbid.,, 1947,25, 417.

    Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Chemistry, Andhra University, Waltair

    V. V. Sreerama Murti & T. R. Seshadri

Authors
  1. V. V. Sreerama Murti
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. T. R. Seshadri
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

Murti, V.V.S., Seshadri, T.R. Nuclear oxidation in flavones and related compounds. Proc. Indian Acad. Sci. (Math. Sci.) 29, 221–226 (1949). https://doi.org/10.1007/BF03172451

Download citation

  • Received:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF03172451

Keywords

Search

Navigation