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Nencki’s reaction with cresols

Summary

The condensation of cresols with acetic, propionic and butyric acids was tried under conditions of Nencki’s reaction employing anhydrous zinc chloride as the condensing agent. Onlyo-cresol gave rise to both theortho- andpara-substituted derivatives, while them- and thep-cresols produced only theortho-substituted products. The yields varied with the duration of heating.

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References

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Beri, R.M., Gakhar, K.L. & Rao, P.S. Nencki’s reaction with cresols. Proc. Indian Acad. Sci. (Math. Sci.) 33, 88 (1951). https://doi.org/10.1007/BF03172188

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  • DOI: https://doi.org/10.1007/BF03172188

Keywords

  • Oxime
  • Propionic Acid
  • Butyric Acid
  • Cresol
  • Steam Distillation