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Methylation of hydroxy flavonols using methyl iodide and potassium carbonate

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Summary

By the action of methyl iodide and potassium carbonate, quercetin underwent complete methylation, while herbacetin and gossypetin yielded 3∶7∶8∶4′-tetramethyl ether and 3∶7∶8∶3′∶4′-pentamethyl ether respectively. This reagent, therefore, resembles diazomethane in the methylation of the naturally occurring flavonols.

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References

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Authors and Affiliations

  1. Department of Chemistry, Andhra University, Waltair

    P. Suryaprakasa Rao, P. Prabhakara Reddy & T. R. Seshadri

Authors
  1. P. Suryaprakasa Rao
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  2. P. Prabhakara Reddy
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  3. T. R. Seshadri
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Rao, P.S., Reddy, P.P. & Seshadri, T.R. Methylation of hydroxy flavonols using methyl iodide and potassium carbonate. Proc. Indian Acad. Sci. (Math. Sci.) 12, 495 (1940). https://doi.org/10.1007/BF03170712

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  • DOI: https://doi.org/10.1007/BF03170712

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