Skip to main content
SpringerLink
Log in

Surgery mobilises endothelial progenitor stem cells for perioperative tumour vasculogenesis

  • Research Papers
  • Published:
Irish Journal of Medical Science Aims and scope Submit manuscript

Conclusion

Both laparotomy and LPS are associated with significant mobilisation of endothelial progenitor stem cells. Given the role of endotoxin and VEGF in perioperative tumorogenesis, these findings may identify a novel mechanism whereby surgical trauma may potentiate tumour growth. Anti-VEGF MAb abrogates this effect, suggesting a novel strategy for preventing perioperative exacerbations of residual tumour growth.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Author information

Authors and Affiliations

  1. Department of Academic Surgery, Cork University Hospital, Ireland

    E. T. Condon, J. H. Wang, D. O’Malley, N. Aherne & H. P. Redmond

Authors
  1. E. T. Condon
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. J. H. Wang
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. D. O’Malley
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. N. Aherne
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. H. P. Redmond
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

Condon, E.T., Wang, J.H., O’Malley, D. et al. Surgery mobilises endothelial progenitor stem cells for perioperative tumour vasculogenesis. Ir J Med Sci 171 (Suppl 4), 4 (2002). https://doi.org/10.1007/BF03170219

Download citation

  • DOI: https://doi.org/10.1007/BF03170219

Keywords

Search

Navigation