Skip to main content
SpringerLink
Log in

Collecting Duct Carcinoma of the kidney: A case report with variable immunohistochemistry

  • Grand Round
  • Published:
Irish Journal of Medical Science Aims and scope Submit manuscript

Abstract

Background

Collecting duct carcinoma of the kidney is a rare tumour with distinctive clinical and histopathological features. Management of this malignancy remains a challenge because of advanced stage at presentation and aggressive clinical course.

Aims

We describe a case of Collecting Duct Carcinoma with variable immunohistochemistry and review the pathology and management.

Results

Our patient died shortly after commencing systemic chemotherapy.

Conclusion

Advances in immunohistochemistry have aided in diagnosis of this tumour. Early detection and nephrectomy offer the best chance of cure. Newer chemotherapeutic regimens may improve survival in more advanced disease.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  1. Fleming S, Lewi HJE. Collecting duct carcinoma of the kidney,Histopathol 1986;10:1131–41.

    Article  CAS  Google Scholar 

  2. Mostofi FK, Sesterhenn IA, Sobin LH. Histological typing of kidney tumours: International histological classification of tumours, N0.25, Geneva, WHO 1981.

    Google Scholar 

  3. Mancilla-Jimenez R, Stanley RJ, Blath RA. Papillary renal cell carcinoma. A clinical, radiological, and pathological study of 34 cases.Cancer 1976;8:2469–80.

    Article  Google Scholar 

  4. Chao D, Zisman a, Pantuck AJ et al. Collecting Duct Renal Cell Carcinoma: clinical study of a rare tumour.J Urol 2002;167:71–74.

    Article  PubMed  Google Scholar 

  5. Peyromaure M, Thiounn N, Scotte F et al. Collecting Duct carcinoma of the kidney: A clinicopatholgical study of 9 cases,J Urol 2003;170:1138–1140.

    Article  PubMed  Google Scholar 

  6. Dimopoulos MA, Logothetis CJ, Markowitz A et al. Collecting duct carcinoma of the kidney,Br J Urol 1993;71:388.

    Article  PubMed  CAS  Google Scholar 

  7. Thoenes W, Storkel S, Rumpelt HJ, Moll R. Cytomorphological typing of renal cell carcinoma-a new approach.Eur Urol 1990;18:6–9.

    PubMed  Google Scholar 

  8. Antonelli A, Portesi E, Cozzoli A etal. The collecting duct carcinoma of the kidney:a cytogenetical study.Eur Urol 2003;43(6):680–5.

    Article  PubMed  CAS  Google Scholar 

  9. Vecchione A, Galetti TP, Gardiman M et al. Collecting duct carcinoma of the kidney:an immunohistochemical study of 11 cases.BMC Urol 2004;4(11)1471–2490.

    Google Scholar 

  10. Culine S, Oudard B, Duclos E et al. A phase II prospective study of gemcitabine and platin-based combinations as first-line chemotherapy for metastatic Bellini duct carcinoma patients. Results of GETUG study.Proc Am Soc Clin Onc 2005, 4543.

  11. Milowsky MI, Rosmarin A, Tickoo SK et al. Active chemotherapy for collecting duct carcinoma of the kidney:a case report and review of the literature.Cancer 2002;94(1):111–6

    Article  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Depts of Medical Oncology and Histopathology, Mater Misericordiae Hospital, Dublin, Ireland

    R. M. Connolly, P. Downey & J. A. McCaffrey

Authors
  1. R. M. Connolly
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. P. Downey
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. J. A. McCaffrey
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to R. M. Connolly.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Connolly, R.M., Downey, P. & McCaffrey, J.A. Collecting Duct Carcinoma of the kidney: A case report with variable immunohistochemistry. Ir J Med Sci 175, 66–68 (2006). https://doi.org/10.1007/BF03169177

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF03169177

Keywords

Search

Navigation