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In vivo natural-abundance17O/1H MRI of rhesus monkey brain with whole-body scanner and homebuilt multinuclear accessory

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Abstract

The construction of an accessory to commercial whole-body magnetic resonance imaging (MRI) scanners that provides multinuclear capability is described. The multinuclear system has access to all clinical pulse sequences and is not limited by the frequency range of the commercially available “spectroscopic package.” The accessory was used for17O studies with a homebuilt birdcage resonator and a low-noise preamplifier. In vivo17O images of a rhesus monkey brain were obtained. The homebuilt birdcage was transparent to radio-frequency irradiation of the scanner’s body coil at1H frequency allowing consecutive acquisitions of1H and17O images and their superposition. The results demonstrate the potential of17O/1H imaging with whole-body scanners.

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Author notes

  1. M. Kempka

    Present address: Institute of Physics, Adam Mickiewicz University, Poznań, Poland

Authors and Affiliations

  1. Department of Physiology and Biophysics, University of Illinois at Chicago, 835 South Wolcott Avenue, 60612-7342, Chicago, IL, USA

    J. Hankiewicz, M. Kempka & D. Fiat

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  1. J. Hankiewicz
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  2. M. Kempka
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  3. D. Fiat
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Hankiewicz, J., Kempka, M. & Fiat, D. In vivo natural-abundance17O/1H MRI of rhesus monkey brain with whole-body scanner and homebuilt multinuclear accessory. Appl. Magn. Reson. 24, 393–400 (2003). https://doi.org/10.1007/BF03166941

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  • DOI: https://doi.org/10.1007/BF03166941

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