Skip to main content
SpringerLink
Log in

Improvement of spectral resolution by spectroscopic imaging

  • Published:
Applied Magnetic Resonance Aims and scope Submit manuscript

Abstract

We propose to use three-dimensional spectroscopic imaging (SI) to increase the spectral resolution for biological samples for which strong susceptibility effects (or poor magnetic homogeneity) cause significant line broadening. Due to susceptibility effects (or poor field homogeneity) the SI voxel spectra even from a uniform sample are shifted with respect to each other and much less broadened than the total sample spectrum. Realignment of the spectra from individual voxels prior to their coaddition produces a total-volume spectrum with significantly narrower lines.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  1. Callaghan P.T.: Principles of Nuclear Magnetic Resonance Microscopy. Oxford: Oxford University Press 1991.

    Google Scholar 

  2. Callaghan P.T.: J. Magn. Reson.87, 304–318 (1990)

    Google Scholar 

  3. Maudsley A.A., Hlial S.K., Perman W.H., Simon H.E.: J. Magn. Reson.51, 147–152 (1983)

    Google Scholar 

  4. Jakob P.M., Kober F., Pohmann R., Haase A.: J. Magn. Reson. B110, 278–283 (1996)

    Article  Google Scholar 

  5. Meininger M., Jakob P.M., von Kienlin M., Koppler D., Bringmann G., Haase A.: J. Magn. Reson.125, 325–331 (1997)

    Article  ADS  Google Scholar 

  6. Ebel A., Soher B.J., Maudsley A.A.: Magn. Reson. Med.46, 1072–1078 (2001)

    Article  Google Scholar 

  7. Mueller S., Aue W.P., Seelig J.: J. Magn. Reson.65, 332–338 (1985)

    Google Scholar 

  8. Sersa I., Macura S.: J. Magn. Reson.135, 466–477 (1998)

    Article  ADS  Google Scholar 

  9. Li B.S., Regal J., Gonen O.: Magn. Reson. Med.46, 1049–1053 (2001)

    Article  Google Scholar 

  10. Tyszka J.M., Mamelak A.N.: J. Magn. Reson.159, 213–218 (2002)

    Article  ADS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Condensed Matter Physics, Jožef Stefan Institute, Jamova 39, 1000, Ljubljana, Slovenia

    I. Serša

  2. Department of Biochemistry and Molecular Biology, Mayo Graduate School, Mayo Clinic and Mayo Foundation, Rochester, Minnesota, USA

    S. Macura

Authors
  1. I. Serša
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. S. Macura
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

Serša, I., Macura, S. Improvement of spectral resolution by spectroscopic imaging. Appl. Magn. Reson. 27, 259–266 (2004). https://doi.org/10.1007/BF03166319

Download citation

  • Received:

  • Revised:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF03166319

Keywords

Search

Navigation