Abstract
Various methods for evaluating bone mineral in appendicular, and axial bone or in the whole skeleton have recently become available. As bone mineral is one of the major determinants of bone strength, its exact measurement should be useful for the diagnosis of osteoporosis, as well as for the prediction of fracture risk and monitoring of therapeutical response.
The aims of this paper are to review the fundamental performance of bone mineral measurements, the improvements in DXA systems, and the progress in site-specific bone mineral instruments for the radius and calcaneus used in Japan, and to introduce diagnostic criteria for primary osteoporosis, and report on annual rates of bone loss in Japanese females.
Similar content being viewed by others
References
Japanese Ministry of Public Health and Welfare. 1995.
Consensus Development Conference. Diagnosis, prophylaxis, and treatment of osteoporosis.Am J Med 94:646–650, 1993.
Inoue T, Kushida K, Miyamoto S, Sumi Y, Orimo H, Yamashita G. Quantitative assessment of bone density on X-ray picture.J Jpn Orthop Ass 57: 1923–1936, 1983.
Matsumoto C, Kushida K, Yamazaki K, Imose K, Inoue T. Metacarpal bone mass in normal and osteoporotic Japanese women using computed X-ray densitometry.Calcif Tissue Int 55: 324–329, 1994.
Hayashi Y, Yamamoto K, Fukunaga M, Ishibashi T, Takahashi K, Nishii Y. Assessment of bone mass by image analysis of metacarpal bone roentgenograms: A quantified digital image processing (DIP) method.Radiation Med 8: 173–178, 1990.
Yuh I, Yamamoto I, Ohnaka Y, Takada M, Nakajima K, Masuda K, et al. Measurement of the calcaneal bone mineral content; correlation with total body bone mineral content.J Jpn Soc Bone Morphom 3: 127–131, 1993. (in Japanese)
Kin K, Kushida K, Yamazaki K, Okamoto S, Inoue T. Bone mineral density of the spine in normal Japanese subjects using dual-energy X-ray absorptiometry: Effect of obesity and menopause state.Calcif Tissue Int 49: 101–106, 1991.
Fujii Y, Tsutsumi M, Tsunenari T, Fukase M, Yoshimoto Y, Fujita T, et al. Quantitative computed tomography of lumbar vertebrae in Japanese patients with osteoporosis.Bone Miner 6: 87–94, 1989.
Fujii Y, Miyauchi A, Takagi Y, Goto B, Fujita K. Fixed ratio between radial cortical volume and density measured by peripheral quantitative computed tomography (pQCT) regardless of age and sex.Calcif Tissue Int 56: 586–592, 1995.
Yamazaki K, Kushida K, Ohmura M, Sano M, Inoue T. Ultrasound bone densitometry of the os calcis in Japanese women.Osteoporosis Int 4: 220–225, 1994.
Genant HK, Engelke K, Fuerst T, Glüer C-C, Grampp S, Harris ST, et al. Non invasive assessment of bone mineral and structure: State of the art.J Bone Miner Res 11: 707–723, 1996.
Wahner HW, Fogelman I. The Evaluation of Osteoporosis: Dual Energy X-ray Absorptiometry in Clinical Practice. London, Martin Dunitz, 1994.
Fukunaga M, Tomomitsu T, Ono S, Otsuka N, Nagai K, Morita K, et al. Determination of vertebral bone mineral density with new dual energy X-ray absorptiometry using multiple detectors: Fundamental studies.Radiation Med 10: 39–43, 1992
Nakamura T, Turner CH, Yoshikawa T, Slemenda CW, Peacock M, Burr DB, et al. Do variations in hip geometry explain differences in hip fracture risk between Japanese and white Americans?J Bone Miner Res 9: 1071–1076, 1994.
Faulkner KG, Cummings SR, Black D, Palermo L, Glüer C-C, Genant HK. Simple measurement of femoral geometry predicts hip fracture: The study of osteoporotic fractures.J Bone Miner Res 8: 1211–1217, 1993.
Tomomitsu T, Sone T, Fukunaga M, Ito M, Ishida Y, Hayashi K. Fundamental study of peripheral QCT (Densiscan-1000).J Jpn Soc Bone Morphom 5: 147–153, 1995. (in Japanese)
Morita R, Yamamoto I, Tsai Y, Yuh I, Kigami Y, Ohta T, et al. A hybrid instrument of US and SXA for the assessment of elastic behavior of bone. Perth International Bone Meeting-Bone Fragility in the Year 2000: Clinical Measurement. West Australia, Feb. 10–13, 1995.
Orimo H, Sugioka Y, Fukunaga M, Mutoh Y, Hotokebuchi T, Gorai I, et al. Diagnostic criteria for primary osteoporosis. Revised version in 1996.J Bone Miner Metab 14: 219–233, 1997. (in Japanese)
Orimo H. Study for prevention of osteoporosis.In Report of Longevity Science Research 1992, vol. 3, pp. 122–124, Tokyo, 1993. (in Japanese)
Fujiwara S, Fukunaga M, Nakamura T, Chen JT, Mizunuma H, Hashimoto T, et al. Age-related changes of bone mineral density in lumbar spine in Japanese women from longitudinal study.J Bone Miner Metab 14: 200, 1996. (in Japanese)
Chung H, Wehrli FW, Williams JL, Kugelmass SD. Relationship between NMR transverse relaxation, trabecular bone architecture, and strength.Proc Natl Acad Sci USA 90: 10250–10254, 1993.
Author information
Authors and Affiliations
Additional information
Based on an invited educational lecture at the 6th Asia and Oceania Congress of Nuclear Medicine and Biology, and the 36th Annual Meeting of the Japanese Society of Nuclear Medicine, Kyoto, October 1996.
Rights and permissions
About this article
Cite this article
Fukunaga, M., Sone, T., Otsuka, N. et al. Bone mineral measurement in Japan. Ann Nucl Med 11, 275–280 (1997). https://doi.org/10.1007/BF03165293
Issue Date:
DOI: https://doi.org/10.1007/BF03165293