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Regional cerebral blood flow and oxygen metabolism in a patient with Korsakoff syndrome

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Abstract

We report a functional neuroimaging study of a patient clinically diagnosed with Korsakoff syndrome. Positron emission tomography (PET) with the15O inhalation method showed decreased regional cerebral blood flow (rCBF) and decreased regional cerebral metabolic ratio for oxygen (rCMRO2) in the bilateral fronto-temporal areas and in the left thalamus. These results suggest that dysfunction of the frontal-thalamic neural network plays a role in the disturbance of Korsakoff syndrome.

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Authors and Affiliations

  1. Division of Neuroimaging Research, Hyogo Institute for Aging Brain and Cognitive Disorders (HI-ABCD), Japan

    Kant Matsuda, Shigeru Yamaji, Kazunari Ishii, Masahiro Sasaki & Hajime Kitagaki

  2. Department of Radiology, Kobe University School of Medicine, Japan

    Setsu Sakamoto

  3. Division of Clinical Neurosciences, Hyogo Institute for Aging Brain and Cognitive Disorders (HI-ABCD), Japan

    Toru Imamura & Etsuro Mori

Authors
  1. Kant Matsuda
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  2. Shigeru Yamaji
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  3. Kazunari Ishii
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  4. Masahiro Sasaki
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  5. Setsu Sakamoto
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  6. Hajime Kitagaki
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  7. Toru Imamura
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  8. Etsuro Mori
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Matsuda, K., Yamaji, S., Ishii, K. et al. Regional cerebral blood flow and oxygen metabolism in a patient with Korsakoff syndrome. Ann Nucl Med 11, 33–35 (1997). https://doi.org/10.1007/BF03164755

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  • DOI: https://doi.org/10.1007/BF03164755

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