Abstract
MR images and three dimensional surface images (3-D images) using N-isopropyl-p-[I-123] iodoamphetamine (I-123 IMP) were obtained in a patient who acknowledged using thinner and amphetamine. While MR images could not find any definite abnormality, 3-D images with I-123 IMP demonstrated multifocal defects. 3-D images with I-123 IMP might be able to detect an early abnormality in brain perfusion in a drug abuser.
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Jacobs IG, Roszier MH, Kelly JK, et al: Cocaine abuse: neurovascular complications.Radiology 170: 223–227, 1989
Kohriyama K, Hori H, Murai Y, et al: Optic neuropathy induced by thinner sniffing.J UOEH 11: 449–453, 1989
Tumeh SS, Nagel JS, English RJ, et al: Cerebral abnormalities in cocaine abusers: demonstration by SPECT perfusion brain scintigraphy.Radiology 176: 821–824, 1990
Streicher HZ, Gabow PA, Moss AH, et al: Syndromes of toluene stuffing in adults.Ann Intern Med 94: 758–762, 1981
Goldfrank L: Amphetamine overdose. InMedicine for the practicing physician, Second Edition, Hurst JW (ed), Boston, Butterworth, pp 1748–1750, 1988
Rumbaugh CL, Bergeron RT, Scanlan RL, et al: Cerebral vascular changes secondary to amphetamine abuse in the experimental animal.Radiology 101: 345–351, 1971
Kasai T, Sugimura K, Okizuka H, et al: Clinical usefulness of three-dimensional brain imaging with N-isopropyl-p-[123I]iodoamphetamine (IMP).Jpn J Nucl Med 26: 311–317, 1989
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Ohta, H., Komibuchi, T., Nishino, I. et al. Brain perfusion abnormalities in a thinner and amphetamine abuser detected by I-123 IMP scintigraphy. Ann Nucl Med 6, 273–275 (1992). https://doi.org/10.1007/BF03164666
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DOI: https://doi.org/10.1007/BF03164666