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ECG-gated thallium-201 myocardial SPECT in patients with old myocardial infarction compared with ECG-gated blood pool SPECT

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Abstract

We evaluated one of the merits of ECG-gated thallium-201 single photon emission computed tomography (g-T1 SPECT), i.e., the ability to appreciate left ventricular (LV) wall motion. LV wall motion assessed by g-Tl SPECT and by ECG-gated Blood Pool SPECT (g-BP SPECT) was classified into three grades and compared segment by segment. T1-201 uptake by g-Tl SPECT was also classified into three grades and compared with those of wall motion in g-BP SPECT.

Fifty patients with prior myocardial infarction were injected intravenously at rest with 111 to 185 MBq (3 to 5 mCi) of Tl-201. The left ventricular regions were divided into anterior, septal, inferior and lateral segments (50 patients × 4 segments=200 segments in total). The grades of wall motion and Tl-201 uptake detected by g-Tl SPECT correlated well with those of wall motion in g-BP SPECT (94.5% and 85%, respectively).

With g-Tl SPECT it was possible to evaluate left ventricular wall motion, providing clear perfusion images.

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Mochizuki, T., Murase, K., Fujiwara, Y. et al. ECG-gated thallium-201 myocardial SPECT in patients with old myocardial infarction compared with ECG-gated blood pool SPECT. Ann Nucl Med 5, 47–51 (1991). https://doi.org/10.1007/BF03164613

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  • DOI: https://doi.org/10.1007/BF03164613

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