Skip to main content
Log in

Heterochromia iridis nach Kataraktoperation mit Linsenimplantation im Kindesalter — ein Fallbericht

Heterochromia iridis after pediatric cataract surgery with iol implantation — Case report

  • Originalarbeiten
  • Published:
Spektrum der Augenheilkunde Aims and scope Submit manuscript

Zusammenfassung

Problemstellung

Weisen die Irides beider Augen eine deutliche Farbdifferenz auf, so spricht man von Heterochromie. Sie ist manchmal auch nach einer Kataraktoperation bei den Kindern bemerkbar. Wir berichten über Heterochromieaufkommen nach der Operation einer einseitigen kongenitalen Katarakt mit Implantation einer Hinterkammerlinse.

Methoden und/oder Patienten

Bei einem 10 Wochen alten Jungen wurde wegen einer kongenitalen Katarakt des linken Auges eine Kataraktoperation durchgeführt. Es wurde eine vordere und hintere Kapsulorrhexis, dann eine vordere Vitrektomie durchgeführt und eine Hinterkammerlinse in den Kapselsack eingepflanzt.

Ergebnisse

17 Monate nach der Operation wurde erstens eine deutliche Heterochromie festgestellt. Die Iris des operierten Auges wurde dunkler. Diese Veränderung wurde nach 40 Monaten noch deutlicher. Gonioskopisch wurde auch eine stärkere Pigmentierung des Trabekelwerkes ohne Drucksteigerang gefunden.

Schlussfolgerungen

Betrachtet man die physiologische Pigmentierung des nichtoperierten Auges, so ist eine starke Zunahme der Pigmentierung, nicht nur der Iris, sondern auch des Trabekelwerkes 40 Monate nach der Kataraktoperation festzustellen. Das Aufkommen der kataraktinduzierten Heterochromie bei Kindern ist noch unklar.

Summary

Introduction

Heterochromia iridis is an asimetry of iris color. In some children, cataract surgery is associated with darkening of the iris color in the operated eye. We present a case of heterochromia iridis following unilateral pediatric cataract surgery with IOL implantation in 10-Week-old boy.

Methods and/or patients

10-week-old boy was reffered to our department for congenital cataract surgery in his left eye. Anterior and posterior capsulorhexis with anterior vitrectomy were performed. IOL was implanted into the capsular bag.

Results

17 months after surgery the heterochromia was observed with darkening of the iris color in the operated eye. 40 months after surgery the changes in iris color were more pronounced. On gonioscopy pathological trabecular hyperpigmentation was observed in the whole circumference with normal intraocular pressure.

Conclusion

40 months after cataract surgery severe pigmentation not only of the iris but also of the trabecular meshwork was observed. A further investigations are necessary to find out the mechanism of heterochromia incidence after pediatrie cataract surgery.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Literatur

  1. Eagle R (1988) Iris pigmentation and pigmented lesions: an ultrastructural study. Trans Am Ophthalmol Soc 88: 581–7

    Google Scholar 

  2. Wilkerson CR, Syed NS, Fisher MR, Robinson NL, Wallow IH, Albert DM (1996) Melanocytes and iris color: light microscopic findings. Arch Ophthalmol 114: 437–42

    Article  CAS  PubMed  Google Scholar 

  3. Imesh PD, Bindley CD, Khademian Z, Ladd B, Gangnon R, Albert DM et al (1996) Melanocytes and iris color: electron microscopic findings. Arch Ophthalmol 114: 114–7

    Article  Google Scholar 

  4. Diesenhouse MC, Palay DA, Newman NJ, To K, Albert DM (1992) Acquired heterochromia with Homer syndrome in two adults. Ophthalmol 99: 1815–7

    Article  CAS  Google Scholar 

  5. Selen G, Stjernschantz J, Resul B (1997) Prostaglandin-induced iridial pigmentation in primates. Surv Ophthalmol 41 [Suppl 2]: S 125–8

    Article  Google Scholar 

  6. Camras CB, Alm A, Watson PG, Stjernschantz J, for the Latanoprost Study Groups (1996) Latanoprost, a prostaglandin analogue, for glaucoma therapy: efficacy and safety after 1 year of treatment in 198 patients. Ophthalmology 103: 1916–24

    Article  CAS  PubMed  Google Scholar 

  7. Alm A, Stjernschantz J, for the ndinavian Latanoprost Study Group (1995) Effects on intraocular pressure and side-effects of 0.005% latanoprost applied once daily, evening or morning: a comparison with timolol. Ophthalmology 102: 1743–52

    Article  CAS  PubMed  Google Scholar 

  8. Watson PG, Stjernschantz J, for the anoprost study Groups (1996) A 6-month randomized, double-masked study comparing latanoprost with timolol in open-angle glaucoma and ocular hypertension. Ophthalmology 103: 126–37

    Article  CAS  PubMed  Google Scholar 

  9. Wistrand P, Stjernschantz J, Olsson K (1997) The incidence and time course of latanoprost-induced iridial pigmentation as a function of eye color. Surv Ophthalmol 41 [Suppl 2]: S 129–38

    Article  Google Scholar 

  10. Lenart TD, Drack AV, Tarnuzzer RW, Fernandes A, Lambert SR (2000) Heterochromia after pediatric cataract surgery. JAAPOS 4 (1): 40–5

    CAS  Google Scholar 

  11. Schraermeyer U (1993) Does melanin turnover occur in the eyes of adult vertebrates? Pigment Cell Res 6: 193–204

    Article  CAS  PubMed  Google Scholar 

  12. Lindquist NG, Larsson BS, Stjernschantz J, Sjöqvist B (1998) Age-related melanogenesis in the eye of mice, studied by micro-autoradiography of 3H-methimazole, a specific marker of melanin synthesis. Exp Eye Res 67: 259–64

    Article  CAS  PubMed  Google Scholar 

  13. Lindquist NG, Larsson BS, Stjernschantz J (1999) Increased pigmentation of iridial melanocytes in primates induced by a prostaglandin analogue. Exp Eye Res 68: 431–6

    Article  Google Scholar 

  14. Stjernschantz J, Selen G, Ocklind A, Wenzel P, Resul B, Lake S (1996) Prostaglandin-induced increase of iridial pigmentation. Pigment Cell Res [Suppl] 5: 19–20

    Google Scholar 

  15. Summers CG, Letson RD (1992) Is the phakic eye normal in monocular pediatric aphakia? J Pediatr Ophthalmol Strabismus 29: 324–7

    CAS  PubMed  Google Scholar 

  16. Matheny AP, Dolan AB (1975) Changes in eye colour during early childhood: sex and genetic differences. Ann Hum Biol 2: 191–6

    Article  CAS  PubMed  Google Scholar 

  17. Bito LZ, Matheny A, Cruickshanks KJ, Nondahl DM, Carino OB (1997) Eye color changes past early childhood: the Louisville Twin study. Arch Ophthalmol 115: 659–63

    Article  CAS  PubMed  Google Scholar 

  18. Nishi O, Nishi K, Imanishi M, Tada Y, Shirasawa E (1995) Effect of cytokines on the prostaglandin E2 synthesis by lens epithelial cells of human cataracts. Br J Ophthalmol 79: 934–8

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  19. Grierson I, Lee WR, Albert DM (1999) The fine structure of an iridectomy-induced eye color change. Arch Ophthalmol 117: 394–396

    Article  CAS  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to D. Pahor.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Pahor, D., Gracner, B. Heterochromia iridis nach Kataraktoperation mit Linsenimplantation im Kindesalter — ein Fallbericht. Spektrum Augeheilkd 16, 214–216 (2002). https://doi.org/10.1007/BF03164337

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF03164337

Schlüsselwörter

Key words

Navigation