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Morbus Behçet — eine Übersicht mit pharmakotherapeutischem Schwerpunkt

Behçet disease — A review with special consideration of pharmacotherapeutic questions

Illustriert an zwei Fallbeispielen

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Zusammenfassung

Der Morbus Behçet führt bei natürlichem Verlauf, das heißt unbeeinflußt von therapeutischen Maßnahmen, in einem hohen Prozentsatz zur Erblindung. Die Krankheitsaktivität ist jedoch von Patient zu Patient unterschiedlich und bestimmt die Zuordnung zu einer schweren Verlaufsform („Majorform“) oder einer leichten Verlaufs-form („Minorform“). Dementsprechend differenziert muß der Einsatz der immunsuppressiven Therapeutika erfolgen. In der vorliegenden Zusammenfassung werden die Vor- und Nachteile der einzelnen Medikamente unter Berücksichtigung ihrer Nebenwirkungen diskutiert. Es wird an Hand von zwei Fallbeispielen, die die zwei Verlaufsformen des M. Behçet repräsentieren, unser Therapieschema vorgestellt.

Summary

Taking it’s natural course M. Behçet leads to blindness in a high percentage of cases. The activity of the illness varies and can be described by “major”- or “minorforms”. According to the severity of the disease the immunosuppressiv therapy will be administered. In this review the advantages and disatvantages of these immunosuppressiv drugs considering also their side effects shall be discussed. We report on two male patients, who suffer from different forms of the illness, and furthermore we present our own therapeutic regiment.

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Ries, E., Velikay, M., Schauersberger, J. et al. Morbus Behçet — eine Übersicht mit pharmakotherapeutischem Schwerpunkt. Spektrum Augeheilkd 9, 39–42 (1995). https://doi.org/10.1007/BF03163733

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