Skip to main content
Log in

Stevens-Johnson-Syndrom — eine interdisziplinäre Herausforderung

Stevens-Johnson syndrome — an interdisciplinary challenge

  • Kasuistiken
  • Published:
Spektrum der Augenheilkunde Aims and scope Submit manuscript

Zusammenfassung

Wegen einer vermuteten Begleitkonjunktivitis beidseits wurde uns ein 9-jähriges Mädchen mit Herpes-simplex-ähnlichen, mukokutanen Veränderungen im Gesichtsbereich konsiliarisch vorgestellt.

Nach Ausschluss eines Herpes corneae und ausführlicher Exploration ergab sich für uns bereits der Verdacht auf ein mögliches Stevens-Johnson-Syndrom. Zusätzliche Beiträge der Dermatologie und Pädiatrie halfen, die Diagnose abzusichern.

In diesem Fall hatte die interdisziplinäre Zusammenarbeit zur rechtzeitigen Diagnosekorrektur und Therapieanpassung geführt.

Summary

A nine year old girl was admitted to the prdiatric department with herpetiform muco-cutaneous lesions in the facial region. The patient also had an accompanying conjunctivitis. The ophthalmologic examination excluded a herpes corneae infection and further extensive exploration suggested the diagnosis of Stevens-Johnson syndrome. Additional dermatologic and pediatric findings confirmed the diagnosis. This interdisciplinary cooperation led to the correct diagnosis and therapy.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

Literatur

  1. Chan HL, Stern RS, Arndt KA, Langlois J, Jick SS, Jick H, Walker AM (1990) The incidence of erythema multiforme, Stevens-Johnson syndrome, and toxic epidermal necrolysis. A population-based study with particular reference to reactions caused by drugs among outpatients. Arch Dermatol 126 (8): 1103–4

    Google Scholar 

  2. Küper K, Pleyer U, Zierhut M, Thiel HJ (1995) Erythema exsudativum multiforme major. Ophthalmologe 92: 823–828

    PubMed  Google Scholar 

  3. Thiel HJ, Richter U, Pleyer U, Zierhut M, Steuhl KP (1990) Arzneimittelinduziertes Erythema exsudativum multiforme majus mit chronisch-progressivem Verlauf und beiderseitiger Erblindung. Klin Monatsbl Augenheilkd 197: 142–149

    Article  CAS  PubMed  Google Scholar 

  4. Genvert GI, Cohen EJ, Donnenfeld ED, Blecher MH (1985) Erythema multiforme after use of topical sulfacetamide. Am J Ophthalmol 99: 465–468

    Article  CAS  PubMed  Google Scholar 

  5. Rubin Z (1977) Ophthalmic sulfonamide-induced Stevens-Johnson Syndrome. Arch Dermatol 113: 235–236

    Article  CAS  PubMed  Google Scholar 

  6. MacDonald A, Peiwel M (1972) Isolation of herpes virus for erythema multiforme. Br J Med 2: 570–571

    Article  CAS  Google Scholar 

  7. Leaute-Labreze C, Lamireau T, Chawki D, Maleville J, Taieb A (2000) Diagnosis, classification and management of erythema multiforme and Stevens-Johnson syndrome. Arch Dis Child 83: 347–352

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  8. Mondino BJ, Brown SI, Biglan AW (1982) HLA antigens in Stevens-Johnson syndrome with ocular involvement. Arch Ophthalmol 100: 1453–4

    Article  CAS  PubMed  Google Scholar 

  9. Mondino BJ, Brown SI (1981) Ocular ciatricial pemphigoid. Ophthalmology 88: 95–100

    Article  CAS  PubMed  Google Scholar 

  10. Foster CS, Fong LP, Azar D, Kenyon KR (1988) Episodic conjunctival inflammation after Stevens-Johnson Syndrome. Ophthalmology 95: 453–462

    Article  CAS  PubMed  Google Scholar 

  11. Stevens AM, Johnson FC (1922) New eruptive fever associated with stomatitis and ophthalmia: Report on two cases in children Am J Dis Child 24: 526–533

    Article  Google Scholar 

  12. Arstikaitis MS (1973) Ocular aftermath of Stevens-Johnson syndrome: review of 33 cases. Arch Ophthalmol 90: 376–379

    Article  CAS  PubMed  Google Scholar 

  13. Romero-Rangel T, Stavrou P, Cotter J, Rosenthal P, Baltatzis S, Foster CS (2000) Gaspermeable scierai contact lens therapy in ocular surface disease. Am J Ophthalmol 130: 25–32

    Article  CAS  PubMed  Google Scholar 

  14. Ghislain PD, Roujeau JC (2002) Treatment of severe drug reactions: Stevens-Johnson syndrome, Toxic Epidermal Necrolysis and Hypersensitivity syndrome. Dermat Online Journal 8 (1): 5

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to U. Oser.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Oser, U., Pinter, O. & Hausmann, N. Stevens-Johnson-Syndrom — eine interdisziplinäre Herausforderung. Spektrum Augenheilkd 19, 39–41 (2005). https://doi.org/10.1007/BF03163200

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF03163200

Schlüsselwörter

Key words

Navigation