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Postoperative topische Mitomycin Behandlung bei Pterygien

Topical application of mitomycin after operation for pterygium

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Zusammenfassung

Die hohe Rezidiv-Neigung von Pterygien stellt ein generelles Problem dar. Postoperative Zusatzbehandlungen wie lokale Strontium 90 Bestrahlung und Thiotepa Augentropfen sind wegen ihrer Nebenwirkungen nicht unumstritten. Es werden die eigenen Ergebnisse einer prospektiven Studie an 70 Augen vorgestellt und diskutiert, die postoperativ 4mal täglich 0,04% Mitomycin C Augentropfen 14 Tage lang als Zusatztherapie erhielten. Damit konnte die frühere Rezidiv-Häufigkeit von 40% auf 1,5% gesenkt werden.

Summary

The high rate of recurrence is a general problem in treatment of pterygia. Postoperative strontium 90 radiation and topical Thioptepa eye drops are not undisputed due to their rate of complications. Herein our own experiences of a prospective study on 70 eyes are reported and discussed. All eyes got postoperatively 0,04% mitomycin C eye drops 4 times daily for 14 days. We could find a reduction of recurrence from 40% before to 1,5% thereafter.

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Literatur

  1. Berkow JR, Gills JP Jr, Wise JB (1969) Registry of interesting cases: Depigmentation of eyelids after topically administered Thiotepa. Arch Ophthalmol 82: 415

    PubMed  CAS  Google Scholar 

  2. Cameron ME (1966) Geographic distribution of pterygia. Trans Ophthalmol Soc Austr 25: 67

    Google Scholar 

  3. Chayakul V (1987) Prevention of recurrent pterygium by mitomycin C. Fortschr Ophthalmol 84: 422

    PubMed  CAS  Google Scholar 

  4. Gourcuff A, Tassay A, Garron J, Perruchot PJ, Blondel P (1984) Thio-Tepa en collyre pour recidives de pterygion et de neovascularisation de cornee. Bull Soc Ophthalmol Fr 84: 583

    CAS  Google Scholar 

  5. Hayasaka S, Noda S, Yamamoto Y, Setogawa T (1988) Postoperative instillation of low-dose mitomycin C in the treatment of primary pterygium. Am J Ophthalmol 106: 715

    Article  PubMed  CAS  Google Scholar 

  6. Hornblass A, Adler RI, Vukcevich WM, Gombos GM (1974) A delayed side-effect of tropical Thiotepa. Ann Ophthalmol 6: 1155

    PubMed  CAS  Google Scholar 

  7. Ishimaru H (1989) Cytotoxicity of mitomycin C in rabbit eyes. Acta Soc Ophthalmol Jpn 93: 54

    CAS  Google Scholar 

  8. Pico G (1965) Pterygium: Current concepts of etiology and management. Highlights Ophthalmol 8: 247

    Google Scholar 

  9. Singh G, Wilson MR, Foster CS (1988) Mitomycin eye drops as treatment for pterygium. Ophthalmology 95: 813

    PubMed  CAS  Google Scholar 

  10. Singh G (1989) Postoperative instillation of low-dose mitomycin C in the treatment of primary pterygium. Am J Ophthalmol 107: 570

    PubMed  CAS  Google Scholar 

  11. Tarr KH, Constable IJ (1980) Late complications of pterygium treatment. Br J Ophthalmol 64: 496

    Article  PubMed  CAS  Google Scholar 

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Hausmann, N., Diem, W. Postoperative topische Mitomycin Behandlung bei Pterygien. Spektrum Augeheilkd 6, 126–128 (1992). https://doi.org/10.1007/BF03162978

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  • DOI: https://doi.org/10.1007/BF03162978

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