Skip to main content
Log in

Potential contrast agents for magnetic resonance imaging

  • Published:
Applied Magnetic Resonance Aims and scope Submit manuscript

Abstract

The development ofmagneto-pharmaceuticals plays an important role in the extension of nuclear magnetic resonance into diagnostic medicine. That is the reason why fundamental investigations leading to new insights into NMR contrast agents are presently being considered. The synthesis and the proton relaxation rates of some new contrast agents are presented. The high values ofR 1, andR 2 relaxivities of the compounds studied by us are promising for various and novel applications.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  1. Hausser K.H., Kalbitzer H.R. in: NMR in Medicine and Biology. Berlin: Springer 1991.

    Google Scholar 

  2. Magerstadt M., Gansow O.A., Brechbiel M.W.: Magn. Reson. Med.3, 808 (1986)

    Article  Google Scholar 

  3. Engelstad B.L., White D.L., Huberty J.P.: Invest. Radiol.22, 232 (1987)

    Article  Google Scholar 

  4. Smith P.H., Brainard J.R., Morris D.E., Jarvinen G.D., Ryan R.R.: J. Am. Chem. Soc.111, 7437 (1989)

    Article  Google Scholar 

  5. Springer C.S., Xu Y. in: New Developments in Contrast Agent Research (Rinck P.A., Muller R.N., eds.), pp. 13–25. Bordeaux: European Magnetic Resonance Forum 1991.

  6. Chambon C., Clement O., Le Blanche A., Schouman-Claeys E., Frija G.: Magn. Reson. Imaging11, 509 (1993)

    Article  Google Scholar 

  7. Rozenman Y., Zou X.M., Kantor H.L.: Magn. Reson. Imaging9, 933 (1991)

    Article  Google Scholar 

  8. Marchai G., Van Hecke P., Demaerel P.: Am. J. Roentgenol.152, 771 (1989)

    Google Scholar 

  9. Marcus K. in: Ion Solvation, chap. 5. Chichester: Wiley 1985.

    Google Scholar 

  10. Bertini I., Luchinat C., Kowaleski J.: J. Magn. Reson.62, 235 (1985)

    Google Scholar 

  11. Narten A.H., Hahn R.L.: Science217, 1249 (1982)

    Article  ADS  Google Scholar 

  12. Geraldes C.F., Sherry A.D., Brown III R.D., Koenig S.H.: Magn. Reson. Med.3, 242 (1986)

    Article  Google Scholar 

  13. Rozenman Y., Zou X.M., Kantor H.L.: Magn. Reson. Med.14, 31–39 (1990)

    Article  Google Scholar 

  14. Rozenman Y., Zou X.M., Kantor H.L.: Radiology175, 655 (1990)

    Google Scholar 

  15. Gillis P., Koenig S.H.: Magn. Reson. Med.5, 323 (1987)

    Article  Google Scholar 

  16. Majumdar S., Gore J.C.: J. Magn. Reson.78, 41 (1988)

    Google Scholar 

  17. Muller R.N., Gillis P., Moiny F., Roch A.: Magn. Reson. Med.22, 178 (1991)

    Article  Google Scholar 

  18. Woessner D.E.: Mol. Physiol.34, 899 (1977)

    Article  ADS  Google Scholar 

  19. Villringer A., Rosen B.R., Belliveau J.W., Ackerman J.L., Lauffer R.B., Buxton R.B., Chao Y.S., Wedeen V.J., Brady T.J.: Magn. Reson. Med.6, 164 (1988)

    Article  Google Scholar 

  20. Koenig S.H., Spiller M., Brown R.D., Wolf G.L.: Magn. Reson. Med.3, 791 (1986)

    Article  Google Scholar 

  21. Canet E., Revel D., Forrat R., Baldy-Porcher C., De Lorgeril M., Sebbag L., Vallee J.P., Didier D., Amiel D.: Magn. Reson. Imaging11, 1139 (1993)

    Article  Google Scholar 

  22. Marchai G., Van Hecke P., Demaerel P., Decrep E., Baert A.L. in: Liver Imaging (Ferruci J.T., Stark D.D., eds.), pp. 415–424. Boston: Andover Medical Publishers 1990.

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Coroiu, I., Darabont, A. & Demco, D.E. Potential contrast agents for magnetic resonance imaging. Appl. Magn. Reson. 15, 531–538 (1998). https://doi.org/10.1007/BF03162035

Download citation

  • Received:

  • Revised:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF03162035

Keywords

Navigation