Journal of Medical Toxicology

, Volume 2, Issue 3, pp 126–135 | Cite as

Phthalates in food and medical devices

  • Karen Chou
  • Robert O. Wright


Phthalates are ubiquitous environmental chemicals with a broad range of potential adverse health effects. Exposure pathways include air, water, packaged food and household products. Biological effects include disruption of the balance of sex hormones, allergic reactions, and enzyme inhibition. Carcinogenicity is seen in animals. In human studies, phthalates have been associated with poorer sperm quality, the symptomatology of asthma, and shortened AGD. Given the widespread use of phthalates in industrialized countries, further research, particularly on birth outcomes, endocrine disruption and child development are greatly needed.


Phthalate DEHP Phthalate Ester Medical Toxicology Volume Phthalate Exposure 



Butyl benzyl phthalate


Butyl isobutyl phthalate


Butyl benzyl phthalate


Body Weight


Dibutyl phthalate


Di (2-ethylhexyl) phthalate


Diethyl phthalate


Di(isodecyl) phthalate


Diisononyl phthalate


Diisooctyl phthalate


Di(isobutyl) phthalate




Di-n-nonyl phthalate


Di-n-octyl phthalate


Extracorporeal membrane oxygenation


Gastro-intestinal tract


Tolerable intake


Mono-n-butyl phthalate


Monobenzyl phthalate


Maximum Contaminant Level


Mono-3-carboxypropyl phthalate


Monoethylhexyl phthalate


Monoethyl phthalate


Mono-2-ethyl-5-hydroxyhexyl phthalate


Mono-2-ethyl-5-oxohexyl phthalate


Monoisobutyl phthalate


Monomethyl phthalate


Total parenteral nutrition


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Copyright information

© American College of Medical Toxicology 2006

Authors and Affiliations

  • Karen Chou
    • 1
    • 3
  • Robert O. Wright
    • 2
    • 3
  1. 1.Department of Animal Science Environmental Science and Policy ProgramMichigan State UniversityUSA
  2. 2.Harvard Medical SchoolBoston
  3. 3.Harvard School of Public HealthUSA

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