Samenvatting
Lichamelijk onverklaarde vermoeidheid die langer dan één jaar na de curatieve behandeling voor kanker nog aanwezig is, komt voor bij ten minste 25% van de ziektevrije kankerpatiënten en heeft grote gevolgen voor het dagelijks leven. Deze vermoeidheid kan niet meer verklaard worden door de aard van de behandeling (chemotherapie of radiotherapie) of het soort kanker. Hier is het onderscheid zinvol tussen uitlokkende factoren (de behandeling van kanker) en instandhoudende factoren. Diverse factoren kunnen de vermoeidheid in stand houden, zoals verwerkingsproblemen, angst voor een recidief, disfunctionele cognities, onregelmatig slaap-waakritme, over- of onderactiviteit, en irreële verwachtingen van de omgeving. Beïnvloeding van deze factoren door middel van cognitieve gedragstherapie leidt tot vermindering van vermoeidheid.
Literatuur
Servaes P, Gielissen MFM, Verhagen S, Bleijenberg G. The course of severe fatigue in disease-free breast cancer patients: A longitudinal study. Psycho-Oncology 2007;16:787-95.
Bower JE, Ganz PA, Desmond KA, Bernaards C, Rowland JH, Meyerowitz BE, et al. Fatigue in long-term breast carcinoma survivors: A longitudinal investigation. Cancer 2006;106:751-8.
Servaes P, Verhagen C, Schreuder BH, Veth RP, Bleijenberg G. Fatigue after treatment for malignant and benign bone and soft tissue tumors. J Pain Symptom Manag 2003;26:1113-22.
Hjermstad SD, Fosså SD, Oldervoll L, Jacobsen AB, Loge JH. Fatigue in long-term Hodgkin’s disease survivors: A follow-up study. J Clin Oncol 2005;23:6587-95.
Gielissen MF, Schattenberg AV, Verhagen CA, Rinkes MJ, Bremmers ME, Bleijenberg G. Experience of severe fatigue in long-term survivors of stem cell transplantation. Bone Marrow Transplant 2007;39:595-603.
Servaes P, Verhagen C, Bleijenberg G. Fatigue in cancer patients during and after treatment: Prevalence, correlates and interventions. Eur J Cancer 2002;28:27-43.
Prue G, Rankin J, Allen J, Gracey J, Cramp F. Cancer related fatigue: A critical appraisal. Eur J Cancer 2006;42:846-63.
Bower JE, Ganz PA, Aziz N, Fahey JL. Fatigue and proinflammatory cytokine activity in breast cancer survivors. Psychosom Med 2002;64:604-11.
Bower JE, Ganz PA, Aziz N. Altered cortisol response to psychologic stress in breast cancer survivors with persistent fatigue. Psychosom Med 2005;67:277-80.
Bower JE, Ganz PA, Dickerson SS, Petersen L, Aziz N, Faley JL. Diurnal cortisol rhythm and fatigue in breast cancer survivors. Psychoneuroendocrinology 2005;30:92-100.
Geinitz H, Zimmermann FB, Thamm R, Keller M, Busch R, Mills M. Fatigue in patients with adjuvant radiation therapy for breast cancer: Long-term follow-up. J Cancer Res Clin Oncol 2004;130:327-33.
Smets EM, Visser MR, Willems GA, Garssen B, Schuster UA, De Haes JC. Fatigue and radiotherapy: (B) experience in patients 9 months following treatment. Brit J Cancer 1998;78:907-12.
Loge JH, Abrahamsen AF, Ekeberg O, Kaasa S. Fatigue and psychiatric morbidity among Hodgkin’s disease survivors. J Pain Symptom Manag 2000;19:91-9.
Bleiker EM, Pouwer F, Ploeg HM van der, Leer JW, Ader HJ. Psychological distress two years after diagnosis of breast cancer: Frequency and prediction. Patient Educ Couns 2000;40:209-17.
Amir M, Ramati A. Post-traumatic symptoms, emotional distress and quality of life in long-term survivors of breast-cancer: a preliminary research. J Anxiety Disord 2002;16:191-206.
Young KE, White CA. The prevalence and moderators of fatigue in people who have been succesfully treated for cancer. J Psychsom Res 2006;60:29-38.
Mast ME. Correlates of fatigue in survivors of breast cancer. Cancer Nurs 1998;21;136-42.
Bower JE, Ganz PA, Desmond KA, Rowland JH, Meyerowitz BE, Belin TR. Fatigue in breast cancer survivors: Occurrence, correlates, and impact on quality of life. J Clin Oncol 2000;18:743-53.
Broeckel JA, Jacobsen PB, Horton J, Balducci L, Lyman GH. Characteristics and correlates of fatigue after adjuvant chemotherapy for breast cancer. J Clin Oncol 1998;78:907-12.
Servaes P, Verhagen S, Bleijenberg G. Determinants of chronic fatigue in disease-free breast cancer patients: A cross sectional study. Ann Oncol 2002;13:589-98.
Pinto BM, Frierson GM, Rabin C, Trunzo JJ, Marcus BH. Home-based physical activity intervention for breast cancer patients. J Clin Oncol 2005;23:3577-87.
Gielissen MFM, Witjes JA, Verhagen S, Bleijenberg G. The effects of cognitive behaviour therapy in severely fatigued disease-free cancer patients compared to patients waiting for cognitive behaviour therapy: A randomised control trial. J Clin Oncol 2006;24:4882-7.
Milne HM, Wallman KE, Gordon S, Courneya KS. Effects of a combined aerobic and resistance exercise program in breast cancer survivors: A randomized controlled trial. Breast Cancer Res Treat 2008;108:279-88.
Dirksen SR, Epstein DR. Efficacy of an insomnia intervention on fatigue, mood and quality of life in breast cancer survivors. J Adv Nurs 2008;61:664-75.
Gielissen MFM, Verhagen S, Bleijenberg G. Cognitive behaviour therapy for fatigued cancer survivors: Long term follow-up. Br J Cancer 2007;97:612-8.
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Hoogleraar, klinisch psycholoog en hoofd van het Nijmeegs Kenniscentrum Chronische Vermoeidheid, Universitair Medisch Centrum St Radboud, Nijmegen.
Onderzoeker-psycholoog, KWF-fellow, Nijmeegs Kenniscentrum Chronische Vermoeidheid, Universitair Medisch Centrum St Radboud, Nijmegen.
Klinisch psycholoog en universitair docent, Nijmeegs Kenniscentrum Chronische Vermoeidheid, Universitair Medisch Centrum St Radboud, Nijmegen.
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Bleijenberg, G., Gielissen, M. & Knoop, H. Cognitieve gedragstherapie bij vermoeidheid na kanker. BIJB 25, 51–57 (2009). https://doi.org/10.1007/BF03087619
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DOI: https://doi.org/10.1007/BF03087619